L11 ethics Flashcards

1
Q

Use of animals in teaching

A
  • The 3 Rs in Pharmacology practicals
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2
Q
  • The 3 Rs in Pharmacology practicals
A

– Replacement - alternatives to animals considered / adopted
* computer simulations, biochemistry
– Reduction – minimise number of animals used
* staff perform dissections
– Refinement - minimise pain & distress, enhance wellbeing
* experienced staff
* experiment design
* environmental enrichment

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3
Q

– Replacement -

A

alternatives to animals considered / adopted * computer simulations, biochemistry

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4
Q

– Reduction

A

– minimise number of animals used
* staff perform dissections

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5
Q

– Refinement

A
  • minimise pain & distress, enhance wellbeing
  • experienced staff
  • experiment design
  • environmental enrichment
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6
Q

Use of animals in teaching: alternatives

A
  • Computer simulations: work and fast response but forgettable
  • Biochemistry-type experiments: tissue culture and test tubes
  • Plastination: tissue with plastic polymer.
  • Filmed practicals
  • Demonstrations
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7
Q
  • Computer simulations
A

– always ‘work’, fast response, convenient
– ‘forgettable’,  understanding of biological systems

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8
Q
  • Biochemistry-type experiments
A

– cell culture, test tube

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9
Q
  • Plastination
A

– biological tissue specimens preserved with plastic polymer – plastinated specimens retain tissue textures and structures

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10
Q

Moral reasoning in the conduct of science

A
  • Sensitivity
  • Reasoning
  • commitment
  • perseverance
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11
Q
  • Moral sensitivity
A

Recognizing potential actions, their impact on others, and how those affected would perceive these actions.

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12
Q

Moral Reasoning:

A

Judging the moral rightness of a course of action.

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13
Q

Moral Commitment:

A

Prioritizing moral values over personal values when making decisions.

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14
Q

Moral Perseverance:

A

Overcoming obstacles to implement the chosen moral course of action.

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15
Q

Principles of bioethics

A
  • Respect for autonomy
  • Non-maleficence
  • Beneficence
  • Justice
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16
Q
  • Respect for autonomy
A

– respect for persons,right to self-determination bioethics

17
Q
  • Non-maleficence
A

bioethics
– an obligation to not inflict harm on others

18
Q
  • Beneficence
A

bioethics
Acting for the benefit of others and society. mercy kindness and charity

19
Q
  • Justice
A

– fairness, equitable treatment

20
Q

Importance of Scientific Integrity:

A

–Scientific knowledge relies on repeated observations and experiments.
–Fabrication or falsification of data can lead to wasted resources, misguided public health policies, and a loss of public trust in science.

21
Q

Shared Values in Science:

A

The sources emphasize honesty, accuracy, efficiency, and objectivity as crucial values for maintaining scientific integrity

22
Q

Rules Governing Scientific Conduct:

A

Professional codes, government regulations, institutional policies, and personal convictions all contribute to guiding ethical scientific practices.

23
Q

National Health and Medical Research Council (NHMR):

A

The NHMR defines scientific misconduct as fabrication, falsification, or plagiarism, excluding honest errors or differences in interpretation.

24
Q

Costs of Misconduct:

A

Corruption of the scientific record, financial costs, damage to reputation, and potential harm to patients and society as consequences of misconduct.

25
* Fabrication
make up results and data
26
* Falsification
manipulating reseach materials and processes or change or omit data so research is not accurately representive
27
Plagiarism
Appropriation of anothers ideas without credit.
28
Describe FIVE methods that may be used to falsify results obtained in clinical trials.
Trials are too short Only test on ideal patients Test drug against somethings that is rubbish like placebo or a low dose of something else Stopping Trials Early to Exaggerate Results “Trials that stop late” Trials that change outcome after finished.