L1: Skeletal system Flashcards

1
Q

What are bones?

A

Calcified connective tissue.

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2
Q

How many bones are found in the body?

A

206

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3
Q

What are the functions of bones?

A

1) Support body & shapes it (framework for the body)
2) Protection of certain organs e.g. skull protects brain.
3) gives attachment to muscles & joints
4) Long bones provide levers for muscles to move joints
5) Formation of blood cells in red marrow.
6) Store & provide body with minerals; Calcium & phosphorus in emergencies.

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4
Q

What are bones classified according to?

A

According to:

A. Position.
B. Development.
C. Structure.
D. Shape.

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5
Q

Classification of bones according to position

A

Axial and appendicular

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6
Q

What is the axial skeleton?

A

skull, vertebral column, Sternum & Ribs

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7
Q

What is the appendicular skeleton?

A

Bones of upper and lower limbs

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8
Q

Describe the vertebral column

A

has 32-33 vertebrae, divided into:

1) Cervical (neck): 7 cervical vertebrae.
2) Thoracic (chest): 12 thoracic vertebrae.
3) Lumbar (low back): 5 lumbar vertebrae.
4) Sacrum: 5 fused sacral vertebrae.
5) Coccyx (tail): 3-4 fused coccygeal vertebra

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9
Q

What is the function of the thoracic cage?

A

It protects heart & lungs & allows breathing

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10
Q

What does the thoracic cage consist of?

A

1) Sternum: anteriorly.
2) Ribs: 12 pairs laterally.
3) 12 Thoracic vertebrae: posteriorly.

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11
Q

Compare between the upper limb and lower limb

A
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12
Q

What is the mechanism of formation of intramembranous bones?

A

The condensed mesenchymal tissue → undergoes bone formation directly

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13
Q

What are examples of intramembranous bones?

A

 shaft of clavicle

 skull cap

 Bones of face.

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14
Q

What is the mechanism of formation of intra-cartilaginous bones?

A
  • The condensed mesenchymal tissue → chondrification first to form a cartilaginous model
  • Then bone is deposited in this model
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15
Q

What are examples of intra-cartilaginous bones?

A

All bones of limbs except shaft of clavicle.

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16
Q

Compare between cancellous (spongy) bones and compact bones

A
17
Q

What are bones classified into according to ossification?

A

Intramembranous and intra-cartilaginous bones

18
Q

What are bones classified into according to structure?

A

Cancellous (spongy) and compact

19
Q

What are bones classified into according to shape and give examples for each one?

A
20
Q

What are the parts of a long bone?

A

A long bone consists of 2 ends & a shaft.

21
Q

What is (epiphysis)?

A

The end of long bone.

22
Q

What is the epiphyseal Cartilage?

A
  • a hyaline cartilaginous plate separate the end from
    the shaft
  • It is the site of growth in length of bone.
  • It ossifies at a certain age forming epiphyseal
    line.
23
Q

What is the diaphysis and what is it composed of?

A
  • The shaft of long bone
  • Composed of:
     a cylinder of compact bone with a cavity
     Medullary cavity contains bone marrow.
     Bone marrow occupies the marrow cavity in long & short bones & cancellous bone in flat & irregular bones:
  • At birth, marrow is red & hematopoietic.
  • At 7 years of age, yellow marrow begins to appear in distal bones of limbs.
24
Q

What is the metaphysis?

A

Wide expanded end of shaft close to epiphyseal cartilage.

25
Q

What is the periosteum and what is its function?

A
  • A fibrous membrane covering Shaft.

- responsible for growth of bone in thickness

26
Q

What is the blood supply of long bones?

A

Nutrient artery: Passes through nutrient canal

Periosteal arteries

Metaphyseal arteries

Epiphyseal arteries

NB. The epiphyseal plate is avascular (= doesn`t have blood supply) & is supplied by diffusion.

27
Q

❖ A 67-year-old woman presented to the emergency department with 4-month history of worsening lower back pain.

❖ There was no history of trauma or falls.

❖ She completed her investigations with serology and radiology.

A

❖ Based on the mentioned history and investigations, the patient was diagnosed with severe osteoporosis.

28
Q

What are the main cells responsible for bone formation and resorption?

A
  • osteoblast cell is responsible for bone formation
  • while osteoclast is responsible for bone resorption
29
Q

What are the two main hormones responsible for calcium deposition and removal from bones?

A
  • calcitonin is responsible for calcium deposition in bone
  • while parathormone is responsible for mobilization of calcium from bone