L1 - Introduction to GI Flashcards
Summarise the GI tract intrinsic sensory pathways
- submucosal and myenteric plexus
- enteric reflexes regulating motility, secretion and blood flow
Describe what stimuli will activate the extrinsic vagal afferents?
Low mechanical stimuli
- thermal
- chemical
Cell bodies of vagal afferents are situated
Nodose ganglion
Central terminal of vagal aferents is found in the…
Brainstem nucleus tractus solitarius
Stroking of gastric mucosa will trigger the release of…
Serotonin (5HT) into the lamina propia of the epithelium.
Small amount into lumen of the gut
What type of innervation is the visceral peritoneum
under
- autonomic innervation
Describe pain felt in the visceral peritoneum
pain is deep, dull and poorly defined
What type of innervation is the parietal peritoneum under
Somatic innervation
Describe pain felt in the parietal peritoneum
pain is sharp, well localised rebound tenderness - pain felt even after hand is lifted guarding - board like rigidity
Explosive onset of pain indicative of…
Perforation of viscus (appendix or colon) or sudden ischaemia (e.g. mesenteric)
Rapid onset on pain may be indicative of…
Acute inflammatoin
e.g. appendicitis, cholecystitis
Gradual progress pain may be indicative of..
Peritonitis
Describe colic pain
Contraction of smooth muscle against an obstruction causes a cyclical on-off pain.
Intervals are severe.
Patient may roll around in pain
Descirbe biliary colic
Gradual onset, then constant.
So not true colic
Peritonitis
- inflammation of peritoneum
- general or localised
- tenderness, guarding and rebound tenderness
- caused by acid form perforated ulcer
- caused by bile from biliary system