L1: Death Flashcards
Def of Death
- Death is irreversible cessation of life, and it is a process not an event.
Def of Somatic Death (Clinical Death)
- Complete and irreversible cessation of vital functions of brain, heart and lungs (the tripod of life)
Phases of Death
1st Phase: Somatic Death (Clinical Death)
2nd Phase: Molecular Death (Cellular Death)
Charcters of Somatic Death
what happens to tissues & Cells after somatic death? and what does it depend on?
- Tissues and cells continue to survive for variable periods of time, depending upon their oxygen requirements.
- After somatic death, Tissues and cells can respond to chemical and electrical stimuli
- Pupils also dilate and constrict.
- Organs can be removed during this “physiological gap” from the cadavers for transplantation.
Dx of Somatic Death
what are simulating conditions to Somatic Death?
Def of Molecular Death (Cellular Death)
It is the ultimate death of all cellular elements.
Characters of Molecular Death
Time of living of various tissues after Somatic Death
It is reported that nervous tissue dies rapidly.
- Vital centers of brain die in about 5 minutes
- While muscle tissue lives up to 3 to 4 hours after cessation of circulation.
when is Molecular Death completed?
- Within 2 to 4 hours of somatic death
- Can be confirmed by absence of any response to an electrical, thermal or chemical stimulus in tissues.
MLI of distinction between somatic and molecular Death
Types of Signs of death
- Immediate Changes (Somatic Death)
- Early Changes (Molecular Death)
Immediate Changes of Death
- Insensibility and Loss of Voluntary Power.
- Irreversible Cessation of Circulation and Respiration.
- Brain/Brainstem Death
- Cerebral/Cortical Death
Characters of Cortical/Cerebral Death
- Brainstem is intact
- With continuous heart sounds and respiration
- No muscular movement with generalized flaccidity.
Def of Cortical Death
- Severe brain damage, which does not involve the brainstem, may result in a persistent vegetative state “Living Cadaver”.
Characters of patients with Cortical Death
These patients:
- Breathe spontaneously
- Open and close their eyes
- Swallow
- Make facial grimaces
- do have a preserved sleep-wake cycle.
- However, they show no behavioral evidence of awareness (Patient does not speak or obey commands).
is EEG enough to diagnose death?
No
Dx of Cortical Death
Caracters of Brainstem Death