Kv channel gating

Question 1

how does voltage changes lead to gating of an ion channel?

Answer 1

charged residues eperenc a force due to voltage feild, so moves so change in confromation ofn the channel

Question 2

how are K+ channels selective?

Answer 2

of specific size so need to shead waters of hyration, to squese htough need to revise

Question 3

what is the Knock on model

Answer 3

that two K+ are in the channel at anyone time with water between then, there are 4 binding sites.

Question 4

what is N-type inactivation of a channel

Answer 4

some Kva channels can block the open pore Nterminal some beta subunits act in the same way