Kreb's Cycle Flashcards
1
Q
Where does the kreb’s cycle occur?
A
Mitochondrial Matrix
2
Q
What happens in the Kreb’s Cycle?
A
- Acetyl CoA
- Enters circular pathway from link reaction
- (if acetyl CoA is formed from fatty acids or amino acids then it enters kreb’s cycle from other metabolic pathways)
- 4C Oxaloacetate accepts Acetyl fragment from Acetyl CoA forming 6C Citrate
- Coenzyme A is released
- Citrate converted back to oxaloacetate through series of oxidation and reduction reactions
3
Q
How is Oxaloacetate regenerated?
A
- Decarboxylation of Citrate (2 CO2 released)
- Oxidation (dehydrogenation) of citrate (H atoms reduce 3 NAD and 1 FAD molecules)
- Phosphate transferred from one of the 5C intermediates (after decarboxylation) to ADP forming ATP molecule
4
Q
What are the products for the Kreb’s Cycle?
A
- 1 ATP
- 2 CO2
- 1 FADH2
- 3 NADH