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IHO final > Krafts > Flashcards

Krafts Flashcards

1
Q

What are the markers for hodkins lymphoma?

A

CD15 and CD30

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2
Q

what are the types of hodkins?

A 
Nodular- good and lacunar cells 
lymphocyte rich- uncommon best prog
Mixed- bad and classic RS eosin 
lymphocyte-depleted- rare worst prog
nodular Lymphocyte prodominate- good
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3
Q

What is lymphoma?

A

Neoplastic prolif that forms a mass in LN or extramedullary

- skips around

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4
Q

What is the classic presentation of NHL?

A

weights loss , fever and night sweats

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5
Q

What is ass with marginal zone lymphoma?

A

helicobacter pylori

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6
Q

What dz shows CD5 and its weird?

A

SLL or CLL

Ritchers cells

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7
Q

what is the prognosis of diffuse large cel lymphoma?

A

bad

extranodal involvent and grows fast

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8
Q

what is the translocation and increase TF of mantle cell?

A

11:14

Cyclin D

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9
Q

What is the translocation and TF of follicular lymphoma?

A

18:14

BCL-2

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10
Q

what is the translocation and TF of Burkitts lymphoma?

A

8:14

c-myc

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11
Q

What are the clinical findings of CLL?

A

older than 40
asymptoms at first
Organ infiltrate
Hypogammaglobulinemia

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12
Q

What cells are positive for TRAP?

A

Hair cell leukemia
Men 5:1
no CD5
prognosis is good

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13
Q

What is more common in children?

A

ALL
Which is TDT +
T is worse prog

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14
Q

What are the lab findings for Myeloma?

A

M-spike
IgG is most of time and IgA sometimes
NEVER IgM
- bence jone protein in urine

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15
Q

what cells are ass with Myeloma?

A

Russel bodies

Rouloaux too

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16
Q

what is waldenstrom macroglobulinemia?

A

IgM

- visual changesa nd retinal thrombosis

17
Q

what is the classic triad of myeloma?

A

bone pain (80%)
renal failure
anemia

IHO final (7 decks)

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