Kleinefelter syndrome Flashcards
1
Q
describe the chromosomal abnormality seen in kleinefelter syndrome
A
47XXY
2
Q
who is affected by kleinefelter syndrome
A
boys
3
Q
how does kleinefelter syndrome occur
A
normally due to non-disjunction during maternal oogenesis
4
Q
describe the features of kleinefelter syndrome
A
poor beard growth wide hips small testicular size long legs female type pubic hair pattern breast development
5
Q
describe what happens in kleinefelter syndrome
A
enter puberty normally
mid puberty –> hypergonadotrophic hypogonadism with decreased testosterone production
generally infertile (azoospermia)
6
Q
what type of sperm production is seen in patients with kleinefelter syndrome
A
azoospermia
