Kisspeptin Flashcards
1
Q
what is kisspeptin?
A
master regulator of the HPG axis
2
Q
how is it the master regulator?
A
it controls the release GnRH (gonadotrophin releasing hormone) which regulates levels of FSH and LH and acts on the gonads
3
Q
what receptors does the Kisspeptin neurons have?
A
receptors for oestrogen, testosterone and androgens
4
Q
describe neuron numbers for kisspeptin during development
A
kisspeptin numbers increases during puberty, and its release also increases during puberty
5
Q
what are mutations of kisspeptin?
A
Idiopathic Hypogonadotrophic hypogonadism - delayed puberty
precocious- early puberty
