KINE 2P09; LECTURE FOUR Flashcards

1
Q

Synapse

A

Specialized junction between neurons where electrical activity in the presynaptic neuron influences the electrical activity of the postsynaptic neuron

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2
Q

Excitatory synapse

A

Bring the membrane potential of postsynaptic neurons closer to the threshold

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3
Q

Inhibitory synapse

A

Bring the membrane potential of postsynaptic neuronS further away from the threshold

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4
Q

Convergence

A

many presynaptic neurons coming to one postsynaptic neuron; combining into one

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5
Q

Divergence

A

One presynaptic neuron flows into many postsynaptic neurons

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6
Q

The release of a ______ mediates communication between cells.

A

chemical messengers

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7
Q

Ionotropic receptor

A

Receptor is an ion channel

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8
Q

Metabotropic receptor

A

receptors that involve proteins and/or second messengers to eventually affect ion channel opening

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9
Q

At an inhibitory synapse, neurotransmitter binds to receptors that elicit a graded hyperpolarization of the postsynaptic neuron called an __________

A

inhibitory postsynaptic potential (IPSP)

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10
Q

Temporal summation: 2+ input signals arrive from the __________in close succession to affect postsynaptic membrane potential

A

same neuron

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11
Q

Spatial summation: 2+ input signals arrive from ______________at about the same time to affect membrane potential

A

differnet neurons

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12
Q

____ is critical for affecting synaptic strength

A

Calcium

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13
Q

Neurotransmitter release from a presynaptic neuron can be altered by:

A
  1. Lack of calcium being pumped out of a neuron
  2. Lack of temporary calcium storage in intracellular organelles during high-frequency stimulation
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14
Q

Axo-axonic synapses:

A

axon terminal of one neuron synapses with axon terminal of another neuron to influence calcium concentration and neurotransmitter release

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15
Q

Presynaptic inhibition:

A

decreases calcium concentration to decrease neurotransmitter release

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16
Q

Presynaptic facilitation:

A

increase calcium concentration to increase neurotransmitter release

17
Q

______ located on the presynaptic axon terminal provides feedback to regulate neurotransmitter release

A

Autoreceptors

18
Q

Neurotransmitters

A

Acetylcholine
Biogenic amines (a. Catecholamines, 1. Dopamine (DA), 2. Norepinephrine (NE) 3. Epinephrine (Epi) B. serotonin C. Histamine)
Amino acids
Neuropeptides
Gasses
Purines
Lipids

the 7 wonders lol

19
Q

Structure of the nervous system…

A

Central Nervous System
Peripheral Nervous System
Afferent
(Somatic sensory (muscle stretch and position)
Visceral sensory (lung/bladder distension)
Special sensory (vision, hearing, etc. )
Efferent
(Somatic Nervous System (control of skeletal muscle)
Autonomic Nervous System (control of heart and vasculature)
Sympathetic and Parasympathetic Nervous Systems

20
Q

Preganglionic neuron

A

Cell body resides in the CNS and projects to autonomic ganglion

21
Q

Postganglionic neuron

A

Cell body resides in autonomic ganglion and projects to tissue

22
Q

Autonomic ganglion

A

Cell cluster outside CNS where pre- and post-ganglionic neurons synapse

23
Q

Sympathetic

A

thoracic and lumbar regions of the spinal cord

fight or flight response

24
Q

Parasympathetic

A

brainstem and sacral region of the spinal cord

est and digest