Kidneys Flashcards

1
Q

What are the three distinct areas of the kidneys?

A

Outer region
Inner region
Innermost draining region

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2
Q

What is the organ of the kidney outer region?

A

Renal cortex

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3
Q

What is the organ in the inner region of the kidney?

A

Renal medulla

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4
Q

What organs make up for the innermost draining region of the kidney?

A

Minor and major calyx, renal pelvis

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5
Q

What is the functional unit of the kidney?

A

The nephron

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6
Q

List the basic structures of the nephron.

A
Glomerulus in bowman’s capsule
Proximal convoluted tubule
Henle’s loop
Collecting duct
Distant convoluted tubule 
Afferent and efferent arterioles
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7
Q

These are a specialized capillary network that are supported by a unique basement membrane.

A

Glomerulus

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8
Q

What is the function of the glomerulus?

A

To filter excess fluid and waste products out of the blood into the urine collecting tubules.

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9
Q

What is the main barrier between urine and blood?

A

The basement membrane

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10
Q

This unit is the beginning of the tubule system. It encases the glomerulus.

A

Bowman’s capsule

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11
Q

What is the tubular function of the kidneys?

A

To reabsorb certain substances back into the bloodstream

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12
Q

What does the proximal tubules does?

A

Reabsorbs ~75% of water and sodium, 95% of glucose, bicarbonate, aa, ions and small molecules.

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13
Q

What is the most metabolically active component of the kidney?

A

The proximal convoluted tubule

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14
Q

The proximal tubules also put into urine substances like what?

A

Urea
Ammonia
Potassium
Hydrogen

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15
Q

What does the distal tubule do?

A

Reabsorbs salt, water, bicarbonate and eliminates uric acid, ammonia, hydrogen

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16
Q

Under the control of what two hormones does the distal tubule function?

A

Anti-diuretic hormone (ADH)

Aldosterone

17
Q

What component of the nephron contains the macula densa for Rene in production?

A

Distal tubules

18
Q

Parts of this cells found in the kidney distal tubules is used in part to synthesize renin

A

Macula densa

19
Q

What is renin?

A

It is a hormone that controls blood pressure

20
Q

When is renin made by the macula densa?

A

When decreased blood pressure has been detected

21
Q

What is another name for ADH?

A

Vasopressin

22
Q

Where is ADH made?

A

In the brain

23
Q

What is the function of ADH?

A

ADH helps in regulating urine output through water volume only

24
Q

How does ADH regulates a decrease in blood volume?

A

A decrease in blood volume results in an increased blood osmolality which will increase ADH and cause a decrease in urine output, increasing blood volume

25
Q

Where is aldosterone made?

A

In the adrenal gland

26
Q

What is the function of aldosterone?

A

Regulate sodium and potassium

27
Q

How does aldosterone regulate sodium and potassium?

A

Increased aldosterone reduces sodium excretion and increases potassium excretion resulting in increased serum sodium and decreased serum potassium

28
Q

What’sthe route of the RAAS in fixing a decrease in blood pressure/volume?

A

Decreased BP/BP - increased renin production - increased angiotensinogen production- increased angiotensin II production - vasoconstriction- increased BP/BV

29
Q

What step is modified in the RAAS in increasing BP/BV with aldosterone production?

A

Vasoconstriction is modified with increased aldosterone production - sodium reabsorption then increased BP/BV