Kidneys Flashcards

1
Q

What are the three distinct areas of the kidneys?

A

Outer region
Inner region
Innermost draining region

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2
Q

What is the organ of the kidney outer region?

A

Renal cortex

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3
Q

What is the organ in the inner region of the kidney?

A

Renal medulla

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4
Q

What organs make up for the innermost draining region of the kidney?

A

Minor and major calyx, renal pelvis

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5
Q

What is the functional unit of the kidney?

A

The nephron

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6
Q

List the basic structures of the nephron.

A
Glomerulus in bowman’s capsule
Proximal convoluted tubule
Henle’s loop
Collecting duct
Distant convoluted tubule 
Afferent and efferent arterioles
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7
Q

These are a specialized capillary network that are supported by a unique basement membrane.

A

Glomerulus

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8
Q

What is the function of the glomerulus?

A

To filter excess fluid and waste products out of the blood into the urine collecting tubules.

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9
Q

What is the main barrier between urine and blood?

A

The basement membrane

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10
Q

This unit is the beginning of the tubule system. It encases the glomerulus.

A

Bowman’s capsule

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11
Q

What is the tubular function of the kidneys?

A

To reabsorb certain substances back into the bloodstream

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12
Q

What does the proximal tubules does?

A

Reabsorbs ~75% of water and sodium, 95% of glucose, bicarbonate, aa, ions and small molecules.

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13
Q

What is the most metabolically active component of the kidney?

A

The proximal convoluted tubule

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14
Q

The proximal tubules also put into urine substances like what?

A

Urea
Ammonia
Potassium
Hydrogen

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15
Q

What does the distal tubule do?

A

Reabsorbs salt, water, bicarbonate and eliminates uric acid, ammonia, hydrogen

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16
Q

Under the control of what two hormones does the distal tubule function?

A

Anti-diuretic hormone (ADH)

Aldosterone

17
Q

What component of the nephron contains the macula densa for Rene in production?

A

Distal tubules

18
Q

Parts of this cells found in the kidney distal tubules is used in part to synthesize renin

A

Macula densa

19
Q

What is renin?

A

It is a hormone that controls blood pressure

20
Q

When is renin made by the macula densa?

A

When decreased blood pressure has been detected

21
Q

What is another name for ADH?

A

Vasopressin

22
Q

Where is ADH made?

A

In the brain

23
Q

What is the function of ADH?

A

ADH helps in regulating urine output through water volume only

24
Q

How does ADH regulates a decrease in blood volume?

A

A decrease in blood volume results in an increased blood osmolality which will increase ADH and cause a decrease in urine output, increasing blood volume

25
Where is aldosterone made?
In the adrenal gland
26
What is the function of aldosterone?
Regulate sodium and potassium
27
How does aldosterone regulate sodium and potassium?
Increased aldosterone reduces sodium excretion and increases potassium excretion resulting in increased serum sodium and decreased serum potassium
28
What’sthe route of the RAAS in fixing a decrease in blood pressure/volume?
Decreased BP/BP - increased renin production - increased angiotensinogen production- increased angiotensin II production - vasoconstriction- increased BP/BV
29
What step is modified in the RAAS in increasing BP/BV with aldosterone production?
Vasoconstriction is modified with increased aldosterone production - sodium reabsorption then increased BP/BV