KIDNEY OVERVIEW Flashcards
1
Q
Major pathways in the kidney
A
Gluconeogenesis
2
Q
The main substrates in in kidney
A
Nonesterified fatty acids (NEFA),
lactate, glycerol, glucose
3
Q
Major products exported by kidney
A
Glucose
4
Q
Specialist enzymes in the kidney
A
Glycerol kinase (minimal amount),
Phosphoenolpyruvate carboxykinase
5
Q
30% of gluconeogenesis in the body occurs here
A
Kidney
6
Q
The enzyme for gluconeogenesis
A
Phosphoenolpyruvate carboxykinase
7
Q
Why does hypoglycemia occur in patients with stage 4 chronic kidney disease?
A
Due to lessened activity of the gluconeogenic pathway
