Kidney Lab Tests Flashcards
If the Lab test is given, give all of the diseases in which the results are significant If the disease is given, give the lab results This information came from Walls handout, please correct me if I'm wrong
Post-Streptococcal Glomerulonephritis
Decreased Complement Levels (C3, C4)
Low C3, but usually not C4 = alt pathway
Lupus Nephritis (2)
May have decreased complement levels
Positive ANA test
Microscopic Polyangiitis
Positive P-ANCA
Amyloidosis
Positive Monoclonal Antibodies in SPEP or UPEP
Membranoproliferative Glomerulonephritis (2)
Hep C > Heb B antibody association
May have decreased levels of C3/C4
Pauci-immune RPGN
Positive P-ANCA
Anti-GBM Test (2)
Positive in: Goodpasture’s and Anti-GBM associated RPGN
ANA Test
Lupus Nephritis
HIV Serologies
Associated with Focal and Segmental Glomerulosclerosis (FSGS)
Endocarditis-associated GN
May have decreased complement levels
Wegener’s Granulomatosis
Positive C-ANCA
Goodpasture’s Syndrome
Positive Anti-GBM test
Cryoglobulinemia (2)
Positive cryoglobulin test
May have decreased C3/C4 levels
Membranous Nephropathy (2)
Associated with Hep B and Hep C
FSGS
HIV serologies
Immune-Complex GN
May have decreased C3/C4 levels
ANCA Tests (3)
Positive in Wegeners (C), Microscopic Polyangiitis (P), Pauci-immune RPGN (P)
Atheroembolic Disease
May have decreased C3/C4 levels
Eosinophilia
Multiple Myeloma
Positive for monoclonal antibodies in SPEP or UPEP
Eosinophiluria (3)
Associated with:
Acute allergic interstitial nephritis, atheroembolic disease… or anything with eosinophilia or pyuria
Hep C Antibody (3)
Mixed Cryoglobulinemia, Membranoproliferative GN, Membranous Nephropathy
Hep B Surface Antigen (3)
Membranoproliferative GN, Membranous nephropathy, Polyarteritis nodosa
Light-chain deposition disease
Positive MC Ab in SPEP or UPEP
Low C3/C4 Levels (7)
Post-Strep GN, Endocarditis GN, Immune Complex GN, MP GN, Lupus, Cryoglobulinemia, Atheroembolic Disease
