Kidney Failure Flashcards
What are the different functions of the kidney?
Homeostatic function
Endocrine function
Excretory function
Glucose metabolism
In kidney failure, how is homeostatic function affected?
Compromised:
- Electrolyte balance
- Acid-base balance
- Volume homeostasis
- Salt and water
What are the consequences of compromised homeostatic function?
Increased potassium
Decreased bicarbonate
Decreased pH
Increased phosphate
Salt & water imbalance
In kidney failure, how is endocrine function affected?
Compromised:
- Erythropoietin production
- 1 alpha-hydroxylase production - vitamin D
What are the consequences of compromised endocrine function?
Decreased calcium
Anaemia
Increased parathyroid hormone
In kidney failure, how is excretory function affected?
Compromised:
- Nitrogenous waste
- Hormones
- Peptides
- “Middle sized molecules”
What are the consequences of compromised excretory function?
Increased urea and creatinine
Decreased insulin requirement
In kidney failure, how is glucose metabolism affected?
Compromised:
- Gluconeogenesis
- Insulin clearance
What does kidney failure increase the risk of?
Cardiovascular disease
