Auditory And Vestibular System Flashcards

1
Q

What type of frequency is captured by vestibular organs?

A

Low frequency motion (movements)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of frequency is captured by hearing organs?

A

High frequency motion (sound)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What comprises sound?

A

Frequency/pitch (Hz): Wave cycles per second - perceived tone
Amplitude/loudness (dB): Sound pressure - subjective attribute correlated with physical strength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the human range of hearing?

A

Frequency: 20-20,000Hz
Loudness. 0 dB to 120 dB sound pressure level (SPL)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the functions of the outer ear?

A

Capture sound and focus it to the tympanic membrane
Modest amplification (10dB) of upper range of speech frequencies due to resonance in canal
Protects the ear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the main function of the middle ear?

A

Mechanical amplification (20-30dB)
Useful for detecting low levels of sound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the functions of the tensor tympani and stapedius muscle?

A

Work to reduce sound (e.g. when things are too loud)
Tensor tympani contracts and stiffens tympanic membrane - reduces vibrations
Stapedius muscle contracts and stops stapes from vibrating as much

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the hearing part of the inner ear?

A

Cochlea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the function of the cochlea?

A

Transduces vibration (through fluid) into nervous impulses
Able to capture frequency and intensity of the sound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Label this image

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Label the image

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the three compartment of the cochlea?

A

Scala vestibuli - bone
Scala tympani - bone
Scala media - membranous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What do the scala vestibuli and tympani contain and what is the substance high in?

A

Perilymph
High in sodium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does the scala media contain and what is the substance high in?

A

Endolymph
High in potassium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where is the hearing organ (Organ of Corti) located?

A

In the scala media of the cochlea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Does the Organ of Corti lie in the vestibular or basilar membrane?

A

Basilar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Describe the arrangement of the basilar membrane

A

Tonotopically arranged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What are the two types of hair cells of the organ of Corti?

A

Inner hair cells (arranged in one line)
Outer hair cells (arranged in lines of three)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the function of the tectorial membrane?

A

Located above hair cells
Allows deflection of hairs which leads to depolarisation of the cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the function of the inner hair cells?

A

Carry 95% of the afferent information of the auditory nerve
Involved in transduction of sound into nerve impulses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the function of the outer hair cells?

A

Carry 95% of the efferent information of the auditory nerve
Involved in modulation of the sensitivity of the response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the name for the ‘hairs’ of the hair cell?

A

Stereocilia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Stereocilia deflect towards the what…?

A

Kinocilium (longest cilium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What does deflection of the stereocilia cause?

A

Opens K+ channels
This depolarises the cell causing release of neurotransmitter to the afferent nerve which then depolarises

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

How are higher amplitudes of sound detected during transduction?

A

Higher amplitudes cause greater deflection of the stereocilia and K+ channel opening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Describe the auditory pathways

A

Spiral ganglions via the vestibulo-cochlear nerve travel to ipsilateral cochlear nuclei (monoaural neurons) in the pons
Auditory information crosses over at the superior olive level -> after this point all connections are bilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Where is the problem located with conductive hearing loss?

A

Outer or middle ear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Where is the problem located with sensorineural hearing loss?

A

Sensory organ (cochlear) or the nerve (auditory nerve)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What are the most and least common types of hearing loss?

A

Sensorineural - accounts for 90% of all hearing loss
Central hearing loss - very rare; originates in brain and brainstem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What is the difference between sudden and progressive hearing loss?

A

Sudden - minutes to days
Progressive - months to years

31
Q

What are some outer ear causes of conductive hearing loss?

A

Wax (cerumen impaction)
Foreign body

32
Q

What are some middle ear causes of conductive hearing loss?

A

Otitis - bubbles can be seen through ear drum suggesting presence of liquid inside the middle ear
Otosclerosis

33
Q

What are the inner ear causes of sensorineural hearing loss?

A

Noise
Presbycusis (old age)
Ototoxicity - e.g. chemotherapy or antibiotics (specifically gentamicin and other aminoglycosides, commonly given for UTIs in hospital)

34
Q

What are nerve causes of sensorineural hearing loss?

A

Acoustic neuroma/vestibular schwannoma - unilateral

35
Q

What does this image show?

A

Acoustic neuroma

36
Q

What are some clinical beside assessments for hearing?

A

Whisper in ipsilateral ear whilst rubbing fingers in contralateral ear
Tuning fork - two tests assess the presence of gross hearing loss - Weber and Rinne test

37
Q

Does hearing loss usually affect the whole frequency range?

A

No, tends to be frequency specific, e.g. high frequencies

38
Q

What is an audiogram?

A

Chart where hearing thresholds are plotted to define if there is hearing loss or not
Note: normal hearing threshold is located between 0-20dB

39
Q

Describe the defining thresholds for hearing loss in dB

A
40
Q

What type of hearing loss does each graph show?

A
41
Q

What are Otoacoustic Emission tests typically used in?

A

Newborn screening and hearing loss monitoring
Does not require a response - unlike audiometry

42
Q

How do Otoacoustic Emissions (OAEs) work?

A

Normal cochlea produces low-intensity sounds called OAEs
Sounds produced specifically by outer hair cells as they expand and contract
Sounds can be detected through a machine

43
Q

What are the treatments for hearing loss?

A

Treat underlying cause - e.g. infection
Hearing aids
Cochlear implants
Brainstem implants

44
Q

What are the inputs of the vestibular system and what detects them?

A

Movement and gravity
Detected by mechanical sensors

45
Q

What are the outputs of the vestibular system?

A

Ocular reflex
Postural control
Help maintain posture and gaze

46
Q

What components make up the vestibular organ?

A

Utricle and saccule (otoliths) are located in the vestibule and are joined to the cochlea (saccule is joined to the cochlea)
Three semicircular canals on each ear - anterior, posterior, lateral
Semicircular canals have an ampulla on one side and are connected to the utricle

47
Q

Label this image

A
48
Q

Where do the hair cells sit in the otolith organs?

A

In the maculae

49
Q

How are the maculae placed in the saccule and utricle organs?

A

Saccule - vertically
Utricle - horizontally

50
Q

What do the maculae contain?

A

Hairs cells
A gelatinous matrix
Otoliths on top - carbonate crystals that help the deflection of the hair cells

51
Q

What causes otolith movement?

A

Linear acceleration and tilt
Utricle - horizontal movement
Saccule - vertical movement

52
Q

Where are the hair cells of the semicircular canals located?

A

In the crista of the ampulla

53
Q

What surrounds the hair cells of the semicircular canals and what is the function of that structure?

A

Cupula - helps with hair cell movement

54
Q

Label this image

A
55
Q

The semicircular canals are high in what fluid?

A

Endolymph - high in potassium

56
Q

What kinds of movement do the semicircular canals detect?

A

Orientation of canals in the head defines three planes
Anterior and posterior canals form a 90 degree angle
Lateral canals are horizontal to the other canals
Work in pairs
Can detect movement at different angles - angular acceleration

57
Q

How are cells depolarised in the vestibular organ?

A

Hair cells have kinocilium and stereocilia
Movement of the endolymph causes deflection of cilia leading to depolarisation

58
Q

Describe hair cell potentials

A

Hair cells have a resting potential which has a basal discharge to the nerve
Movement towards kinocilium causes depolarisation- increase in nerve discharge
Movement away from kinocilium causes hyperpolarisation - reduction in nerve discharge

59
Q

Where do the primary afferent of the vestibular nerve end?

A

Vestibular nuclei of pons

60
Q

What other areas does the vestibular nerve communicate with?

A

Vestibulospinal tract
Abducens nucleus
Medial longitudinal fasciculus (connects 3rd and 6th nerve)
Oculomotor nucleus

61
Q

What are the key functions of the vestibular system?

A

Detect and inform about head movements
Keep images fixed in retina during head movements
Balance

62
Q

What is the vestibular-ocular reflex (VOR)?

A

Keeps images fixed in retina
Connection between vestibular nuclei and oculomotor nuclei
Eye movement in opposite direction to head movement, but same velocity and amplitude

63
Q

What is the purpose of the vestibulo-spinal reflex do?

A

Helps to maintain posture, e.g. when falling

64
Q

How do you categorise vestibular disorders?

A

Timing and laterality:
Acute and unilateral
- Main complaints are imbalance, dizziness, vertigo and nausea
Slow and unilateral or bilateral loss
- Main complaints are imbalance and nausea - no vertigo

65
Q

Give examples of peripheral vestibular disorders

A

Affect vestibular organ and/or VIII nerve:
Vestibular neuritis
Benign Paroxysmal Positional Vertigo (BPPV)
Meniere’s disease

66
Q

Give examples of central vestibular disorders

A

Stroke
Multiple sclerosis
Tumours

67
Q

What is the clinical approach to diagnosis of suspected vestibular disorders?

A
68
Q

What is it called when the eyes change in the laterality of how they move?

A

Skew

69
Q

Name two acute balance disorders

A

Vestibular neuritis
Stroke

HINTS exam useful to differentiate

70
Q

Name an intermittent balance disorder

A

Benign Paroxysmal Positional Vertigo

Dix-Hallpike Test - useful in diagnosis

71
Q

Name a recurrent balance disorder

A

Migraine ( Meniere’s disease)

72
Q

Name two progressive balance disorders

A

Schwannoma vestibular (VIIIth nerve)
Degenerative conditions (MS)

73
Q

Describe the steps of the HINTS exam

A

Head Impulse test
- Horizontal rotational VOR
Nystagmus
- Vestibular organ vs cerebellar/brainstem nystagmus
Test of Skew deviation
- Vertical misalignment - usually absent in peripheral pathology