Kidney

Question 1

Gross features of oncocytoma

Answer 1

Well circumscribed
Mahogany brown or tan or yellow
Central or eccentric stellate scar
Haemorrhage may be present
No necrosis present

Question 2

Syndrome associated with renal oncocytoma and features that make you suspect this

Answer 2

Birt Hogg Dube Syndrome

Multiple oncocytoma and bilateral

Question 3

What are the cells that oncocytoma arise from?

Answer 3

Renal intercalated cells

Also packed with defective respiratory mitochondria which is what gives it that eosinophilic look

Question 4

Chromophobe gross features

Answer 4

Well circumscribed
Unencapsulated
Tan, light brown
Haemorrhage, necrosis or cysts maybe present
Central scar maybe present

Question 5

Chromophobe Rcc microscopic features

Answer 5

Defined cell membranes (plant like or alligator skin)
Fine reticular cytoplasm with eosinophilic tinge
Perinuclear Halos (koilocytic)
Wrinkled, rasinoid nuclei