Key Terms Flashcards
Oil
A lipid that is liquid at room temperature
Lipid
Organic molecule that is relatively insoluble in water and soluble in organic solvents
Fat
A type of lipid that is solid at room temperature
Fatty Acid
A type of lipid consisting of a chain of carbons with a methyl (CH3) group on one end and a carboxyl acid group (COOH) on the other. A fatty acid can either be a “free” fatty acid, or can be attached to another molecule
“Free” Fatty Acid
A fatty acid that is not attached to another molecule
alpha end
The end of a fatty acid, which consists of (COOH)
Delta end
Another name for the alpha (COOH) end
Omega End
The end of the fatty acid chain, which consist of (CH3) group
Chain Length
the number of C in a fatty acid’s backbone
Short-chain FA
s
Medium chain FA
8-12 C’s
Long chain FA
> 12 C’s
Saturated FA
A FA that consists only C-C single bonds
Unsaturated FA
A FA that consist at least one C=C
Monounsaturated FA
Consists of one C=C
Polyunsaturated FA
FA that consist of more than 1 C=C
Lauric Acid
A medium chain FA believed to contribute to increase HDL levels. Increases serum blood cholesterol more than any other FA
Myristic Acid
common saturated FA found in nutmeg butter, palm kernel oil, coconut oil, and butter fat.
Palmitic Acid
Most common saturated FA found in plants and animals. Consumption is believed to increase the risk for cardiovascular disease.
Stearic Acid
saturated FA that contains an 18C chain and is currently believed to lower LDL cholesterol
Oleic Acid
a naturally-cooking unsaturated FA that is thought to decrease LDL cholesterol and increase HDL cholesterol
Cis double bond
A C-C double bond in which the H’s are located on opposite sides of the double bonds
Trans double bond
A C=C in which H’s are located on the same side of the double bond
Elaidic Acid
A primary trans FA found in hydrogenated vegetable oils, goat and cow’s milk, and some meats. Responsible for lowering HDL cholesterol.
Partial Hydrogenation
Process whereby some C=C found in PUSAs are converted to C-C, resulting in the production of a lipid containing saturated and trans fatty acid.
Omega-3 FA
The first double bond is located between the 3 and 4 C’s from omega end (CH3)
Omega-6 FA
The first double bond is located b/t the 6 and 7 C’s from the omega end (CH3)
Linoleic Acid
w-6 FA with 18 C’s and 2 double bonds
Gamma-Linolenic Acid (GLA, 18C)
18 C FA found in primarily in vegetable oil
Linolenic Acid
w-3 acid 18 C’s and 3 double bonds
Elongation
Process whereby C’s are added to FA, increasing chain length
Desaturation
The process whereby C-C single bonds are C=C bonds in FA’s
Desaturase
Enzyme that can insert a (cis) double bond in a FA by removing two H’s from an adjacent pair of C’s
Arachidonic Acid
a long chain, PU v-6 FA produced from linoleic acid
Eicosapentaenoic Acid (EPA)
long chain, PU w-3 FA produced from linolenic acid
Docosahexaenoic Acid (DHA)
a long-chain PU w-3 FA produced from EPA
Eicosanoids
Biologically active compounds - prostaglandins, prostacyclins, thromboxanes, and leukotrienes- synthesized from arachidonic acid and EPA, which are produced from both LA (n-6) ALA (n-3)
Postaglandins
a group of eicosanoids involved in regulation of blood pressure; there are both v-6 and v-3 prostaglandins, having somewhat opposite effects
Prostaglandin I2 (prostacyclin)
an eicosanoid that inhibits platelet activation. Prostacyclin is also an effective vasodilator.
Prostaglandin I3
An eicosanoid that inhibits platelet aggregation. Prostaglandin I3 is a potent vasodilator
Thromboxane A2
eicosanoids that are produced by activated platelets. They stimulate activation of new platelets and increase platelet aggregation.
Vasoconstriction
Narrowing of blood vessels that results from the contraction of the muscular walls of the blood vessels
Vasodilation
Narrowing of blood vessels that results from the relaxation of the muscular walls of the blood vessels
Platelet aggregation
the clumping together o platelets in the blood
Pro-inflammatory
a substance that causes inflammation in the body
Prothrombotic
substance that can lead to an obstruction of one or more blood vessels. Thrombi are also called clots
Anti-inflammatory
substance that decrease inflammation in the body
anti-thrombotic
a substance that decreases the risk of thrombi in the body
Ester bond
an ester is a chemical compound derived from either an organic or inorganic acid. At least one -OH group has been replaced by an O-alkyl group. Esters are typically derived from a COOH group and an alcohol. They are found in most naturally-occurring oils. An ester bond is formed b/t the acid and the O-alkyl group
Esterify
to combine a substance with either an alcohol or an acid to form an ester bond
De-esterify
to remove ester groups
Triglyceride
a lipid composed of a glycerol molecule bonded to three fatty acids
Diglyceride
a lipid made of a glycerol molecule bonded to two fatty acids
Monoglyceride
a lipid made of a glycerol molecule bonded to a single FA
Phospholipid
A type of lipid composed of a glycerol bonded to two FA and a polar head
Polar head group
a phosphate-containing charged chemical structure that is a component of a phospholipid
Polar molecule
a molecule such as water, that has both positively and negatively charged portions
Hydrophilic substance
one that dissolves in or mixes with water
Nonpolar molecule
one that does not have differently charged portions
hydrophobic substance
one that does not dissolve in or mix with water
Amphipathic
both nonpolar (noncharged) and polar (charged) portions
Phosphatidylcholine (lecithin)
A phospholipid that contains choline as its polar head group; commonly added to foods as an emulsifying agent
Sterol
type of lipid with a distinctive mutli-ring structure; a common example is cholesterol
sterol ester
chemical compound consisting of a sterol molecule bonded to a FA via ester linkage
Cholesterol
a sterol found in animal foods and made in the body; required for bile acid and steroid hormone synthesis
Cholesteryl Ester
a sterol ester made of a cholesterol molecule bonded to a FA via an ester linkage