Key Associations 7 Flashcards
t(8;14)?
Burkitt’s lymphoma (c-myc activation)
t(9;22)?
Philadelphia Chr, CML (bcr-abl fusion)
Temporal arteritis?
Risk of ipsilateral blindness due to thrombosis of ophthalmic artery; polymyalgia rheumatica
Testicular tumor?
Seminoma
Thyroid cancer?
Papillary carcinoma
Tumor in women?
Leiomyoma (estrogen dependent, not precancerous)
Tumor of infancy?
Hemangioma (usually regresses spontaneously by childhood)
Tumor of the adrenal medulla (adults)?
Pheochromocytoma (usually benign)
Tumor of the adrenal medulla (kids)?
Neuoblastoma (malignant)
Type of Hodgkin’s?
Nodular sclerosis (vs. mixed cellularity, lymphocytic predominance, lymphocytic depletion)
Type of non-Hodgkin’s?
Diffuse large cell
UTI?
E. coli, Staph saprophyticus (young women)
Viral encephalitis affecting temporal lobe?
HSV-1
Vitamin deficiency (US)?
Folate (pregnant women are at high risk; body stores only 3- to 4-month supply; prevents neural tube defects)
Rheumatoid arthritis + pneumoconiosis?
Caplan’s syndrome