Key Associations

Question 1

Actinic (solar) keratosis

Answer 1

precursor to squamous cell CA

Question 2

acute gastric ulcer associated with CNS injury

Answer 2

Cushing ulcer (hi ICP stimulates acid secretion)

Question 3

acute gastric ulcer associated with severe burns

Answer 3

Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)

Question 4

alternating areas of transmural inflammation and normal colon

Answer 4

skip lesions of Crohn’s

Question 5

Dissecting aneurysm

Answer 5

HTN

Question 6

Abdominal and descending aortic aneurysm

Answer 6

atherosclerosis

Question 7

Ascending aortic aneurysm

Answer 7

Marfan

Question 8

Atrophy of mamillary bodies

Answer 8

Wernicke encephalopathy (B1 def causing ataxia, ophthalmoplegia, confusion)

Question 9

Autosplenectomy (fibrosis and shrinkage)

Answer 9

HbS (sickle cell)

Question 10

Bacteria associated with gastritis, PUD, and stomach cancer

Answer 10

H. pylori

Question 11

Bacterial meningitis (adults and elderly)

Answer 11

N. meningitidis

Question 12

Bacterial meningitis (kids)

Answer 12

Group B Strep agalactiae (newborns), Strep pneumo (kids)

Question 13

Benign melanocytic nevus

Answer 13

Spitz nevus (most common under 20)

Question 14

Bleeding with GP Ib deficiency

Answer 14

Bernard-Soulier dz

Question 15

Adult Brain tumor

Answer 15

mets > GBM (astrocytoma) > meningioma > Schwannoma

Question 16

Breast cancer

Answer 16

infiltrating ductal CA

Question 17

Breast mass

Answer 17

fibrocystic change or CA (postmenopausal)

Question 18

Benign breast tumor

Answer 18

fibroadenoma

Question 19

Primary cardiac tumor in Kids

Answer 19

Rhabdomyoma (often with tuberous sclerosis)

Question 20

Lupus cardiac manifestations

Answer 20

Libman Sacks endocarditis (nonbacterial, both sides of mitral valve)

Question 21

Adult Cardiac tumor

Answer 21

mets #1

myxoma (ball valve in LA) is #1 primary

Question 22

Cerebellar tonsillar herniation

Answer 22

Chiari malformation (progressive hydrocephalus or syringomyelia)

Question 23

Chronic atrophic gastritis (autoimmune)

Answer 23

predisposes to gastric CA

Question 24

Clear cell adenoCA of the vagina

Answer 24

Diethylstilbestrol (DES) exposure in utero

Question 25

Congenital cardiac anomaly

Answer 25

VSD is #1

Question 26

Constrictive pericarditis

Answer 26

TB (worldwide)

SLE (developed)

Question 27

Death in CML

Answer 27

blast crisis (accelerate and transform to ALL or AML)

Question 28

Dementia

Answer 28

1: Alzheimer’s
2: multiple infarct

Question 29

DIC

Answer 29

G- sepsis, OB complication, Cancer, Burn trauma, acute Pancreatitis, Nephrotic (lose Antithrombin III)

Question 30

Hemochromatosis

Answer 30

1: multiple blood transfusions
2: HFE mutation (HH; bronze diabetes)

Question 31

Most common hereditery bleeding disorder

Answer 31

von Willibrand disease (AD)

Question 32

HLA-B27

Answer 32

PAIR (psoriasis, ankylosing spondylitis, IBDs, Reiter’s syndrome)

Question 33

HLA-DR3 or 4

Answer 33

DM 1, RA, SLE

Question 34

Blood transfusion infection

Answer 34

HepC

Question 35

1 lysosomal storage disease

Answer 35

Gaucher dz

Question 36

Neuron migration failure

Answer 36

Kallman syndrome

Question 37

Ovarian tumor (benign, bilateral)

Answer 37

Serous Cystadenoma

Question 38

Ovarian tumor (malignant)

Answer 38

Serous CystadenoCA

Question 39

Cervical motion tenderness

Answer 39

PID (Chlamydia, then gonorrhea post 1-joint arthritis; FHC: liver capsule inflamm, salpingitis can = ectopic pregnancy + infertility)

Question 40

Sites of atherosclerosis

Answer 40

abdominal aorta > coronary > popliteal > carotid

Question 41

Tumor of adrenal medulla (kids)

Answer 41

Neuroblastoma (c-myc; malignant)

Question 42

Viral encephalitis affecting the Temporal lobe

Answer 42

HSV-1