Karius - Sleep & EEG Flashcards

1
Q

gene products that set up circadian rhythm

A
  • CLK
  • BMAL
  • Per
  • CRY
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2
Q

area of the brain where circadian rhythm is generated

A

suprachiasmatic nucleus

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3
Q

area of the brain that controls circadian rhythm and sleep induction/arousal

A

hypothalamus

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4
Q

3 stages of non-REM sleep

A
  • 1
  • 2
  • deep
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5
Q

EEG findings during REM sleep

A

low amplitude, high frequency

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6
Q

most of sleep time is spent in

A

non-REM sleep

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7
Q

nucleus of the hypothalamus that’s impt in sleep induction

A

ventral preoptic area

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8
Q

what binds to DP on meningeal cells?

A

PGD2

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9
Q

what is released from DP cells of meningies?

A

adenosine

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10
Q

what receptoe does adenosine bind to in the VPO

A

2a

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11
Q

what area releases Ach into the geniculate body to induce REM sleep

A

lateral pontine tegmentum

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12
Q

where does the geniculate body send info to to induce REM sleep

A

occipital cortex

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13
Q

what induces muscle paralysis in REM sleep?

A

Locus Ceruleus

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14
Q

the lateral hypothalamus is one of the only sources of what in the brain?

A

Orexin A and B

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15
Q

what NT is released in the locus ceruleus to active LC neurons

A

histamine

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16
Q

LC neurons release what NT to suppress REM sleep?

A

NE

17
Q

waves that occur during quiet wakefulness with eyes closed

A

alpha

18
Q

origin of alpha waves

A

from occipital cortex

19
Q

waves that occur while awake with eyes open

A

beta

20
Q

origin of beta waves

A

frontal, parietal cortex

21
Q

waves ass’d with attention/motor planning

A

gamma

22
Q

waves ass’d with furstration and sleep

A

theta

23
Q

slowest and largest waves

A

delta

24
Q

waves that do not require connection btwn thalamus and ctx

A

delta

25
Q

duration of first sleep cycle

A

70-100 min

26
Q

later sleep cycle avg length

A

90 min

27
Q

REM sleep is characterized by

A

rapid eye movement

28
Q
  • slow, rolling movements of eyes

- EMGs show mm activity

A

stage 1 (N1) sleep

29
Q
  • low voltage EEG

- slowing of EEG freq

A

stage 1 (N1) sleep

30
Q

Stage 2 sleep is known as

A

true sleep

31
Q

EMGs show v quiet mm activity

A

stage 2 (N2) sleep

32
Q
  • increasing EEG voltage
  • slowing of EEG frequency
  • sleep spindles
  • K complexes
A

Stage 2 (N2) sleep

33
Q

EEG sign that someone is truly asleep

A

sleep spindles

34
Q

bursts of alpha-like activity

A

sleep spindles

35
Q
  • increasing EEG voltage

- slowing of frequency with prominent theta and delta waves

A

deep sleep

36
Q
  • rapid side-to-side eye movement

- EMG becomes v quiet

A

REM sleep

37
Q
  • rapid, low voltage EEG

- similar to beta waves

A

REM sleep