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(Farmakologi) > Kapitel 7: Kolinoreceptoraktiverende og -blokerende lægemidler > Flashcards

Kapitel 7: Kolinoreceptoraktiverende og -blokerende lægemidler Flashcards

1
Q

Atropin

A

Reversibel acetylkolin-receptor-antagonist

Indikation:

  • Antidot mod sarin(AChE-hæmmer)
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2
Q

Botulinum toksin type A virkningsmåde

A

Inaktiverer SNAP25 som regulerer fusion af vesikler indeholdende acetylcholin med plasmamembranen.

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3
Q

Fysostigimin

A

Reversibel AChE-hæmmer

Er en tærtier amin(i modsætning til de andre -stigminer). Kan komme over blod-hjerne-barrieren.

Bruges som antidot de muskarin-receptor-antagonister

Bruges mod glaukom: Forbedret afløb for kammervæske

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4
Q

Ipratropium

A

Muskarin antagonist

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5
Q

Malation

A

…

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6
Q

Neostigmin

A

Reversibel AChE-hæmmer

Indikation:

  • Blæreatoni. Kontraherer blæren.
  • Glaukom
  • Myasthenia gravis

Revertering af neuromuskulær blokade: Indirekte displacering af NM-receptor-antagonister

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7
Q

Nikotin

A

Kolinorecptor agonist

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8
Q

Obidoxim

A

…

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9
Q

Pilokarpin

A

Kolinoceptor agonist

Lipidopløselig, elimineres renalt

Indikation:

  • Tør mund. Stimulerer spytsekretionen.
  • Glaukom. Kontraherer m. sfinkter pupilae og m. ciliaris
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10
Q

Pyridostigmin

A

Reversibel AChE-hæmmer

Indikation: Myasthenia gravis

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11
Q

Rivastigmin

A

Reversibel AChE-hæmmer

Forsinker udvikling af Alzheimers

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12
Q

Skopolamin

A

Blokerer muskarine receptorer.

Indikation:

  • Køresyge
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13
Q

Tolterodin

A

Muskarin-receptor-antagonist

Indikation:

  • Overaktiv blære

Bivirkninger:

  • Mundtørhed
  • Akkomidationsparese
  • Takykardi

Obstipation

Vandladningsbesvær

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14
Q

Tropicamid

A

…

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15
Q

Trospium

A

Muskarin-receptor-antagonist

Indikation:

  • Overaktiv blære

Bivirkninger:

  • Mundtørhed
  • Akkomidationsparese
  • Takykardi
  • Obstipation
  • Vandladningsbesvær
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16
Q

Botulinum toksin type A bivirkninger

A
  • Ptose
  • Kvalme
  • Ansigtsødem
17
Q

Botulinum toksin type A indikation

A
  • Cerebral parese hos børn
  • Spasticitet i armen som følge af slagtilfælde
  • Hemifaciale spasmer
  • Blefarospasma
  • Spastisk torticollis
  • Persisterende svær primær aksillær hyperhidrose
  • Kosmetisk mod rynker
18
Q

Donepezil

A

Reversibel AChE-hæmmer

Indikation:

  • Alzheimers
19
Q

Suxametonium

A

…

(Farmakologi) (46 decks)

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