Kandel

Question 1

incidence of schiz throughout the world

Answer 1

1%

Question 2

incidence of schiz among parents, children and siblings of patients with the disease

Answer 2

15%

Question 3

tendency for twins to have same illness

Answer 3

concordance

Question 4

concordance for schizophrenia in monozygotic twins, dizygotic twins

Answer 4

45% in monozygotic and 15% IN DIZYGOTIC TWINS

Question 5

Anatomical abnormalities in imaging of Schiz pts

Answer 5

early: reduction in the blood flow to the left globus pallidus

disturbance in the frontal lobes

cortex of median temporal lobe is thinner and anterior portion of hippocampus us smaller, more on Left

lateral and third ventricles are enlarged,widening of sulci