Kaizen Questions Flashcards
Which drug is least effective with treating acute gout flares?
Colchicine
Naproxen
Prednisone
Probenecid
Probenecid - should be used once flares are gone (uric acid lowering medication)
Everything else is effective
When comparing acetaminophen and naproxen, what difference does naproxen have when compared to acetaminophen?
Naproxen has…
anti-inflammatory effects, have increased risk for CV events, and have potential for GI ulceration
Acetaminophen acts centrally (no CV, GI, or bleeding effects) as naporxen acts more peripherally (having CV, GI, and potential bleeding risks).
What medication is MOST LIKELY going to cause concern when completing a medication reconciliation and a pt is taking vitamins such as A, B12, C & K?
Warfarin (oral anticoagulant) d/t Vitamin K being an antidote for hypoprothrombinemiia and bleeding.
Which antibiotc is seen most as bactericidal in nature and would be most appropraite for an immunocompromised individual who has a potential infx?
Beta lactam ie penicillin
Macrolide ie erythromycin
Tetracycline ie tetracycline
Sulfonamide ie sulfanilamide
Beta lactam - considered to be bactericidal; everything is bacteriostatic and can cause further harm to the pt d/t their poor immune response.
When a patient is on an oral glucocorticoid, what education is most important when they are approaching day 5 of 7 of tx?
Tapering is only necessary when oral GC have been used for >10 days or less than 2-3 weeks
If less than 10 days it is okay to not taper.
Which medication is most appropriate to use as prophylaxis of migraine HAs?
Propanolol
What medication can help delay RAs affect on pts joints?
Methotrexate in combination with NSAID and GC
When would you administer glucococorticoid medications when following normal circadian patterns?
2/3 after the patient wakes up, 1/3 in the afternoon
OR
full dose in the morning
What medications would be contraindicated in pregnancy with a patient who has RA?
Methotrexate - d/t it being a CATEGORY X medication
What lab value is most concerning when elevated for a patient taking exogenous Vitamin A?
LFTs (ALT, AST) as it can cause liver damage at high values
Which vitamin reduces the risk for bleeding?
Vitamin K
A patient w/ actinic keratsoses should expect what to occur while taking the medication fluorouracil?
Tissue ulceration & necrosis should be expected
Healing w/n 6 weeks
Application of drug x2 daily
Severe inflammation should halter tx
Tissue ulceration & necrosis should be expected
Which medication is most likely to cause Ca++ reduction thus further increasing the risk of osteoporosis?
Lisinopril
HCTZ
Calcium carbonate
Prednisone (glucocorticoid)
Prednisone (glucocorticoid) - prolonged tx (>5mg for> 3 mos) is a known r/f for osteoporosis by suppressing osteoblast activity which is responsible for bone formation & new tissue
HCTZ holds onto Ca++ in the DCT
Calcium carb adds Ca++ to the body
Lisinopril has no effect on Ca++ lvls
