kahoot questions Flashcards
Which fiber types transmit information on pain and temperature?
- C fibers
- Abeta fibers
- Adelta fibers
- Ia fibers
Adelta (poorly- myelinated) & C fibers (unmyelinated)
Abeta = Touch (Merkel, …)
Ia fibers = Proprioception (Muscle spindle)
True or False?
In dissociated sensory loss, nociception remains intact while mechanosensory perception is lost.
False
both remain partly intact, depending on where
Which ion is the main substrate for TRP ion channels?
Ca2+
Which is the main source for top-down pain modulation?
- somatosensory cortex
- amygdala
- periaqueductal gray
- spinal dorsal horn
periaqueductal gray
Which is the most prevalent mechanoreceptor in human skin?
- Meissner corpuscles
- Ruffini corpuscles
- Merkel cells
- Pacinian corpuscles
Meissner corpuscles (40%)
Merkel cells (25%), Ruffini corpuscles (20%), Pacinian corpuscles (10-15%)
Inhibitory cortical interneurons make up what mean percentage of the overall cortical neuron count?
25%
Which ganglionic eminence(s) produce(s) cortical interneurons?
- Medial ganglionic eminence
- Caudal ganglionic eminence
- Lateral ganglionic eminence
- Rostral ganglionic eminence
- Medial ganglionic eminence
- Caudal ganglionic eminence
Which interneuron type is particularly effective in suppressing target cell output?
- Chandelier cell
- Martinotti cell
- Non-Martinotti cell
- Translaminar cell
Chandelier cell
Put the developmental stages of interneurons in correct order!
- Radial migration through the layers
- Migration towards the cortex
- Neurogenesis in ganglionic eminence
- Tangential migration through the cortex
- Neurogenesis in ganglionic eminence
- Migration towards the cortex
- Tangential migration through the cortex
- Radial migration through the layers
True or False?
Roughly a third of all interneurons undergo apoptosis (programmed cell death) after settling in the cortex.
True
Sort the steps a BCI takes when operating with the first step on top and the last step at the bottom of the list!
- Feature translation
- Signal acquisition
- Device output and feedback
- Feature extraction
- Signal acquisition
- Feature extraction
- Feature translation
- Device output and feedback
What pathway is primarily active when flexing an arm muscle?
- Corticobulbar pathway
- Corticospinal pathway
Corticospinal pathway
Corticobulbar pathway controls muscles of face, head and neck.
Name a possible feature that could be derived from a modality of signal acquisition!
- amplitude of ERP
- frequency of ERP
- frequency power spectra (e.g. sensorimotor rhythms)
- firing rates of individual cortical neurons
True or False?
Every BCI requires a translation algorithm that translates already extracted and processed data.
False
Not all BCIs require it (e.g. artificial neural networks)
True or False?
The stimulation of a single motor neuron in primary motor cortex elicits activity only in a single correspondent muscle.
False
Which hormone levels lead to temporary increase in hippocampal volume?
- High estrogen, low progesterone
- Low estrogen, low progesterone
- High estrogen, high progesterone
- Low estrogen, high progesterone
High estrogen, low progesterone
True or False?
There is consensus on the role of estrogen on memory.
False
Which of the following is not a symptom of Premenstrual Dysphoric Disorder according to the DSM-5?
- Moodiness
- Hot flashes
- Acne
- Stomach cramps
hot flashes
Choose the correct statements!
- Progesterone decreases anxiety.
- Estrogen improves mood.
- Cortisol reactivity decreases in the luteal phase.
- Amygdala activity increases in the luteal phase.
- Progesterone decreases anxiety.
- Estrogen improves mood.
- Amygdala activity increases in the luteal phase.
Which of the following is not a phase of the menstrual cycle?
- Fovear phase
- Luteal phase
- Follicular phase
- Ovulation
Fovear phase
Which of the following eye movements fulfill the function of shifting gaze?
- Vergence
- Saccade
- vestibulo-ocular movements
- smooth pursuit
- Vergence
- Saccade
- smooth pursuit
vestibulo-ocular movements and optokinetic reflex for stabilizing gaze
True or False?
Abduction and adduction are executed by the superior and inferior rectus muscles.
False
by medial and lateral rectus muscle
Which of the following cranial nerves innervate muscles of the ipsilateral eye?
- oculomotor (III) and trochlear (IV)
- optic (II) and abducens (VI)
- trochlear (IV) and abducens (VI)
- oculomotor (III) and abducens (VI)
oculomotor (III) and abducens (VI)
During a saccade to the left, which of the following structures are activated?
- left lateral rectus muscle
- right abducens nucleus
- right oculomotor nucleus
- left medullary reticular formation
- left lateral rectus muscle
- right oculomotor nucleus
- left medullary reticular formation
True or False?
We can orient our eyes in response to an auditory stimulus due to topographically organized maps in the superior colliculus.
True
Which of the following processes are part of the amyloid cascade?
- Cleavage of APP by alpha-secretases and gamma-secretase
- Excessive accumulation of Abeta peptides
- Disruption of normal synaptic transmission
- Cleavage of APP by beta-secretase and gamma-secretase
- Excessive accumulation of Abeta peptides
- Disruption of normal synaptic transmission
- Cleavage of APP by beta-secretase and gamma-secretase
True or False?
Injections with an Abeta-based antigen are an example of passive immunotherapy against Abeta.
False
passive immunotherapy: injection of antibodies or cytokines
Aducanumab mainly binds to …
- APP
- Monomers
- Oligomers
- Soluble monomers
Oligomers
Which of the following was the most common adverse event reported in the phase 3 trials EMERGE and ENGAGE?
- ARIA-H microhemorrhage
- Headache
- ARIA-E
- Nasopharyngitis
ARIA-E
True or False?
Aducanumab received accelerated FDA-approval due to beneficial effect on cognitive decline in MCI or mild dementia.
False
no clear link bw achieved reduction in Aβ plaques & cog.
improvement
Which of the following is not a feature of Alzheimer’s disease pathogenesis?
- Decreased Firmicutes species in gut
- Increased GABA in CNS
- Highly active microglia
- Chronic secretion of proinflammatory cytokines in the gut
increased GABA in CNS
True or False?
The release of lipopolysaccharides in the gut induces blood-brain barrier permeability.
True
What percentage of overall serotonin and GABA are produced in the gut, respectively?
- 75% of serotonin, 20% of GABA
- 50% of serotonin, 95% of GABA
- 90% of serotonin, 50% of GABA
- 10% of serotonin, 60% of GABA
90% of serotonin, 50% of GABA
Choose all the correct statements regarding Ghrelin.
- Ghrelin induces weight gain.
- Ghrelin receptors are expressed in the CNS.
- Ghrelin level decrease causes depression.
- Ghrelin is implicated in hippocampal neurogenesis.
- Ghrelin induces weight gain.
- Ghrelin receptors are expressed in the CNS.
- Ghrelin is implicated in hippocampal neurogenesis.
True or False?
Improved sanitation in early life has been shown to increase the risk of Alzheimer’s disease.
True
Order events leading to Alzheimer’s disease according to gut-brain connections.
- Leaky blood-brain barrier and neuroinflammation
- Increased gut inflammation and leaky gut
- Amyloid plaque aggregation
- Gut dysbiosis
- Gut dysbiosis
- Increased gut inflammation and leaky gut
- Leaky blood-brain barrier and neuroinflammation
- Amyloid plaque aggregation
True or False?
A feedforward control system needs a representation of the system’s internal state.
True
According to the UCT theory, what is the cognitive outcome of cerebellar damage called?
- Dystonia of thought
- Ataxia of thought
- Dysmetria of thought
- Arrhythmia of thought
Dysmetria of thought
According to the Guell, Hoche & Schmahmann (2014) paper, what did patients with dysmetria of thought find difficult?
- Understanding a new sentence
- Constructing a new sentence given context constraints
- Evaluating the syntactic correctness of a sentence
- Constructing a new sentence by inferring it from context
Constructing a new sentence by inferring it from context
True or False?
The cerebellar output to the basal ganglia is thought to preferentially influence the direct pathway.
False