KA6 U1

Question 1

What are all biochemical reactions that occur in a cell

Answer 1

Cell metabolism

Question 2

What are metabolic pathways

Answer 2

Metabolic pathways are pathways of enzyme catalysed reactions that are integrated and controlled

Question 3

Metabolic pathways can have two steps

Answer 3

Reversible and irreversible

Question 4

What else can metabolic pathways have

Answer 4

Alternative routes that can by pass steps in a pathway

Question 5

Anabolic reaction

Answer 5

Build up of large molecules and require enerfy

Question 6

Catabolic

Answer 6

Break down of lathe molecules into smaller molecules releases energy

Question 7

A metabolic pathway can be controlled by what of an enzyme

Answer 7

The presence or absence of a particular enzyme

Question 8

What are enzymes coded by

Answer 8

Genes

Question 9

Each step in a metabolic pathway is controlled by

Answer 9

A specific enzyme

Question 10

If appropriate enzymes are present

Answer 10

The pathway proceeds smoothly

Question 11

If a enzyme is missing

Answer 11

The pathways comes to a halt

Question 12

Activation energy

Answer 12

Energy required to start a chemical reaction

Question 13

What is the active site

Answer 13

Location where substrate molecules bind and chemical reaction takes place

Question 14

What is the shape of an active site specific to

Answer 14

The complementary shape of the substrate

Question 15

What type of attraction do the substrate molecules have for the the active site

Answer 15

Chemically attracted

Question 16

What do substrate molecule have for enzymes

Answer 16

High affinity for active site

Question 17

Once the substrate binds to the active site what happens?

Answer 17

The active site shape changes slightly, to better fit the substrate this is induced fit

Question 18

After the substrate bind the active site what happens

Answer 18

Affinity lowers and leaves the active site

Question 19

Factors affecting enzyme activity

Answer 19

Temp
PH
Concentration of substrate

Question 20

The presence of what or removal of something else drive a sequence of reactions in a direction

Answer 20

The presence of a substrate or removal of a product

Question 21

What do inhibitors do

Answer 21

Slow down the rate of enzyme controlled reaction to bring it to a halt

Question 22

Inhibitors can be used for what

Answer 22

Used to stop enzyme binding to substrate

Question 23

What is the results of this

Answer 23

Inhibitors can directly control profess of metabolic pathways are pathways or reduce rate of reaction

Question 24

3 types of inhibition

Answer 24

Competitive
Non competitive
Feed back

Question 25

Competitive inhibitors

Answer 25

• Has smaller molecular structure to the substrate •binds at the active site prevent substrate from binding

Question 26

How to reverse a competitive inhibitors

Answer 26

Increase concentration of substrate

Question 27

Non competitive inhibitors

Answer 27

•Different structure from substrate molecules • bind away from active site •changes shape of active site prevent substrate from binding

Question 28

How can non competitive inhibitors be reversed

Answer 28

They can’t

Question 29

Feedback inhibition

Answer 29

It occurs when the end product in the metabolic pathway reaches a critical concentration

Question 30

Then what does the end product inhibition do

Answer 30

The end product then inhibits an earlier enzyme blocking the pathway do ask prevents further synthesis of the end product