Juvenile Idiopathic Arthritis & Other Common Acute Childhood Orthopaedic/Rheumatic Presentations Flashcards
What is the common feature of juvenile idiopathic arthritis?
Swelling or limitation of motion of the joint, accompanied by heat, pain or tenderness, lasting at least 6 weeks.
What are the three subgroups of juvenile idiopathic arthritis and their prevalence?
- Oligoarticular/pauciarticular: 4 joint or less (50-60%)
- Polyarticular: more than 5 joints (30%)
- Less common types (10%)
Pathology
Synovial joint lining becomes inflamed and thickened, causing pain, redness, swelling and joint stiffness.
What percentage of oligoarticular cases are ANA positive?
80%
When is the peak onset of oligoarticular JIA?
1-3 years of age
What percentage of polyarticular cases are ANA positive?
50%
When is the peak onset of polyarticular JIA if RF positive?
Adolescence, persisting into adulthood
When is the peak onset of polyarticular JIA if RF negative?
1-3 years of age
How does polyarticular JIA if RF positive affect the joints?
Symmetric multiple small and large joints
How does polyarticular JIA if RF negative affect the joints?
Often asymmetric multiple small and large joints
What percentage of enthesitis related arthritis cases are HLA B27 positive?
80%
How does enthesitis related arthritis affect the joints?
Assymetric, large joints, including axial skeleton
When is the onset of psoriatic arthritis most common?
Preschool and age 10
What joints are commonly affected in psoriatic arthritis?
Small and large joints, especially DIP
What medical managements are often used for JIA?
- NSAIDs
- Corticosteroids
- Disease modifying anti-rheumatic drugs
- Biologics
- Intra-articular steroid injections