JRA

Question 1

Still disease accounts

For how many percent in the disease

Answer 1

20% of JRA

Question 2

age

Answer 2

skin manif in 40% of young patients age 7-25 yo.

Question 3

lesions

Answer 3

evansecnet; non pruritix salmon pink macular papular lesions on the trunk and extremities may precede onset of joint manif by months.

High ferritin levelsX neutrophilic panniculitis

Question 4

tx

Answer 4

Steroid sparing agents

Refrafory dx- tx w biologic agents as desc pulse methylpred an cyclophosphamide.
anakinra and canakinumab may be helpful.

Question 5

a rare condition char by bilateral distal polyarthritis, flexion contractures. cutaneous nodules, sclerodactylitis, thickened palmar fascia, reynaud phenomenon.

Biopsy : fibroblastic prolif w collagenous stroma varying from smooth muscle actin positive cellular fasicles to paucicellular areas w randomly arranged spindle or stellate cells.

tx: immunosupp agents typically methotrexate and oral steroid

Answer 5

Fibroblastic rheumatism

Question 6

Symmetric syndovitis may also be a manif of what syndrome

Answer 6

Blau syndrome

Question 7

Relapsing polychondritis tx

Answer 7

nsaid steroid trad immunosup.

cyclophosphamide extremely severe dxZ

Question 8

Relapsing polychondritis histo

Answer 8

RP(N)

Neutrophilic infiltrate in perichondrium.

Question 9

Magic syndrome Is ancombination of what 2 disease?

Answer 9

Behcet disease and relapsing polychondritis.