Jaundice G

Question 1

jaundice

Answer 1

liver issues causing yellowing of the skin

Question 2

what types of bilirubin is present in the different types of jaundice

Answer 2

pre - unconjugated

post - conjugated

intra - both

Question 3

neonatal jaundice timings

Answer 3

early <24hrs

intermediated 24hrs-2 weeks

prolonges >2 weeks

Question 4

early causes

Answer 4

always pathologic

haemolysis, sepsis

Question 5

intermediate causes

Answer 5

physiological
breast milk
sepsis
haemolysis

Question 6

early/intermediate unconjugated investigations

Answer 6

urine + blood cultures
blood group
blood film
G6PD assay

Question 7

unconjugated complication

Answer 7

kernicterus - when bilirubin crosses BBB causing encephalopathy

Question 8

management of unconjugated jaundice

Answer 8

phototherapy

Question 9

prolonged causes

Answer 9

conjugated:
extra hepatic obstruction
neonatal hepatitis

unconjugated:
hypothyroidism
breast milk

Question 10

important investigation in prolonged jaundice

Answer 10

split bilirubin to differentiate between unconjugated and conjugated

Question 11

causes of extra hepatic obstruction

Answer 11

biliary atresia
choledochal cyst
malformation of bile ducts
alagille syndrome

Question 12

biliary atresia

Answer 12

congenital fibre-inflammatory disease of bile ducts leading to destruction of extra-hepatic bile ducts

Question 13

signs of biliary atresia

Answer 13

pale stools
dark urine
liver failure

Question 14

management

Answer 14

kasai portoenterosotmy

Question 15

what would be sign of haemolyis in babies

Answer 15

bruising