jaundice Flashcards
scleral icterus indictes serum bilirubin of
3 mg/dl
second place to look for icterus after sclera
Undersurface of tongue
DD for yellowing of skin
carotenoderma
quinacrine
exposure to phenols
difference between icterus and carotenoderma
sparing of sclera
carotenoderma localised to palms,soles,forehead,nasolabial folds
causes of discoloration of sclera
jaundice
quinacrine
serum bilirubin rarely exceeds ________ in hemolytic disorders
5mg/dl
Higher bilirubin levels in hemolytic disorders
acute hemolysis in sickle
coexistent hepatocellular or renal dysfunction
UDPGT can be induced by
phenobarbital
serum bilirubin levels in inherited unconjugated hyperbilirubinemias
Criggler najjar type 1 : >20mg/dl
CN type 2: 6-25mg/dl
gilbert < 6mg/dl
Presentation of dubin johnson and rotor syndrome
asymptomatic hyperbilirubinemia in second decade of life
H/O arthralgia and myalgia predating jaundice
acute hepatitis- viral or drug induced
Jaundice with right upper quadrant pain and shaking chills
ascending cholangitis
choledocholithiasis
temporal and proximal muscle wasting with jaundice
cirrhosis
pancreatic cancer
Tender hepatomegaly
Viral hepatitis
alcoholic hepatitis
amyloidosis
Right heart failure
Ascites with jaundice
cirrhosis
malignancy with intraperitoneal spread
Screening test for wilson disease
ceruloplasmin
Extrahepatic cholestatic conditions presenting as false negatives in USG
partial common bile duct obstruction
cirrhosis
PSC
cholestatic variant of hepatitis B and C
fibrosing cholestatic hepatitis
fibrosing cholestatic hepatitis occurs in
solid organ transplanted patients
vanishing bile duct syndrome
liver transplant rejection
GVHD
sarcoidosis
chlorpromazine
Causes of AIDS cholangiopathy
CMV
cryptosporidiosis
