Jan 24th Content Flashcards
Weight in hand sensed by fibers to move said weight
mechanical tension
Idea that lower loads align more metabolites for growth
metabolic stress
Muscle Damage
not necessary for hypertrophy
Metabolic Stress mechanisms
feel the burn, getting a pump, higher reps, shorter rest
Muscle Damage mechanisms
eccentrics, full ROM, novelty
Mechanical Tension mechanisms
progressive overload (system force production) & mind-muscle connection (muscle force production)
Base of hypertrophy period
mechanical tension
What contributes to fatigue?
Metabolites
Motor unit fatigue
one after the other until the complete end of the set for overall growth
Studies didn’t give opportunity for growth beyond what is maximal due to
BFR and high load RT
Letting pressure go during BFR rest periods releases
metabolites
Post-exercise BFR study purpose
determine whether BFR at conclusion of set could augment muscle hypertrophy
End product of glycolysis
Lactate
Does lactate accumulate?
Yes
ATP Hydrolysis
ATP + H2O <– ATPase –> ADP + Pi + H
Post-exercise BFR study hypothesis
applying BFR post-exercise would not induce greater hypertrophy
Post-exercise BFR pilot study looked to see if there were ______ with what protocol?
metabolites; 70%, one set to failure, cuff inflated as soon as failure begins
Post-exercise BFR study results
cuff attenuated growth, metabolites did nothing, more discomfort in cuff group
Anabolic benefits of venous BFR study suggested that
swelling could be anabolic
Fluid into the muscle cell could bring in
proteins/nutrients
Elevated plasma lactate levels via exogenous lactate infusion study purpose
investigate whether lactate could exhibit cell signaling properties in combo with contractile activity
Elevated plasma lactate levels via exogenous lactate infusion study design
two sessions of unilateral leg extension with simultaneous venous infusion of sodium lactate or isotonic saline; followed by 3 warm-up sets and 6 sets at 75%
Elevated plasma lactate levels via exogenous lactate infusion study results
muscle lactate and pH had drastic increases in the muscle; no difference in lactate or saline conditions
Exercise –>
mTor
mTor –>
S6K1
S6K1 –>
increases MPS
Elevated plasma lactate levels via exogenous lactate infusion study discussion
Maybe needs to be refined, or more, or injected directly into muscle; may reduce exercise while increasing lactate to see if there is a response
Elevated plasma lactate levels via exogenous lactate infusion study limitations
no potential to augment due to maximal exercise protocol