Feb 7th Content Flashcards
What is the only compound the body can use for energy driven processes
ATP
What is the bioenergy currency in the cells of all tissues
ATP
Energy is stored between
2nd and 3rd phosphate groups
Three Energy Systems
ATP-PCr, Glycolytic, Oxidative Metabolism
ATP-PCr occurs in
the cytoplasm
Which energy system has the fastest rate of ATP
ATP-PCr
Which energy system has the shortest duration for producing ATP
ATP-PCr
ATP-PCr system forms ATP with
creatine phosphate without oxygen
Glycolytic occurs in
the cytoplasm
Which energy system has a moderate rate and duration of ATP production
Glycolytic
Glycolytic energy system breaks down
CHO
CHO broken down by the glycolytic system is stored
in the muscle or glucose delivered to the blood
Cho broken down by the glycolytic system s used to
resynthesize ATP
Oxidative Metabolism occurs in
the mitochondria
Which energy system has the slowest rate of ATP production
Oxidative Metabolism
Which energy system has the longest duration at which ATP can be produced
Oxidative Metabolism
Oxidative Metabolism includes
KC and ETC
Oxidative Metabolism forms ATO from
breakdown of fatty acids using oxygen in the mitochondria
Energy derived from reactions are used to drive
activity
Fat breakdown –>
ATP
ATP fuels
actomyosin cross-bridge cycling
Actomyosin cross-bridge cycling reaction catalyzed by
mATPase
Actomyosin cross-bridge cycling yields
energy + ADP + Pi
All three energy systems are
active at any given time
Contribution of energy systems is primarily dependent on
intensity of activity and duration of activity
ATP-PCr prevents energy depletion by
quickly reforming ATP from ADP + Pi
1 ATP is produced from
1 PCr
Enzyme to break apart PCr
creatine kinase (CK)
Creatine kinase is highest in which fibers
T2b > T2a > T1
The energy from the breakdown of PCr is used for
regenerating ATP
How much ATP does the body store at any given time
80-100 g
ATP is stored in
muscle on myosin head
ATP concentrations during experimentally induced muscle fatigue
only slightly decrease (50-60% of pre-exercise levels)
ATP-PCr through CP and creatine kinase reaction serves as
energy reserve for rapidly replenishing ATP
ADP + creatine phosphate <–
creatine kinase
creatine kinase –>
ATP + creatine
Oral bioavailability of ATP is…
not bioavailable, no reason to supplement
ATP is well maintained during what duration of sprinting
8-10 s
PCr is rapidly depleted during _________ to supply
sprinting; Pi and ADP
Adenylate Kinase (myokinase) Reaction
replenish ATP, important for AMP
AMP is a
powerful stimulant of glycolysis
AMP helps to breakdown more
CHO
2 ADP <–
adenylate kinase
adenylate kinase –>
ATP + AMP
How is the ATP-PCr controlled
law of mass action
ATP + H2O <–
ATPase
ATPase –>
ADP + Pi + H
Buildup of ADP will increase rate of
creatine kinase and adenylate kinase reactions
Contribution of phosphocreatine and aerobic metabolism to energy supply study purpose
examine relationship between metabolic status of muscle before a second sprint ad subsequent performance and changes in muscle metabolites during sprint
Contribution of phosphocreatine and aerobic metabolism to energy supply study methods
2 maximal cycle ergometer sprints, separated by 4 minutes recovery; main trial, 30 s followed by 30 s, 2nd main trial, 30 s followed by 10s