IV. Surface Modifications Flashcards by Marco Ferretti | Brainscape

Q

Surface coatings

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Bioactive surface functionalization - 3 steps

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Bioactive surface functionalization - Proteins diffuses freely at distance of > 2nm

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Bioactive surface functionalization - Protein can bind reversibly (adsorption) and release (desorption) directly at the interface

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Bioactive surface functionalization - Bound prot. can change structurre to maximize surface interactions

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Q

Bioactive surface functionalization - All materials adsorb bioolecules in varying amounts due to:

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Bioactive surface functionalization - Control of physical adsorption of biomolecules

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Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

types

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Bioactive surface functionalization - Introducing charges to biomaterials surface

Exposure to oxidizing agent

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Bioactive surface functionalization - Introducing charges to biomaterials surface

Plasma treatement

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Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Plasma treatement

methods

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Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Coating with a charged polymer

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Bioactive surface functionalization - Limitations of physical adsorption

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Bioactive surface functionalization - Covalent coupling of biomolecules to materials (=chemical adsoroption)

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Q

Bioactive surface functionalization - Covalent coupling of biomolecules to materials (=chemical adsoroption)

Types

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Bioactive surface functionalization - (Bio-)conjugation chemistry

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Bioactive surface functionalization - Silanization of biomaterials

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Bioactive surface functionalization - Surface coupling of biomolecules using a spacer

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Bioactive surface functionalization - Comparison of surface immobilization strategies

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Bioactive surface functionalization - bioinspired strategies

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Bioactive surface functionalization - bioinspired strategies

Nacre

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Bioactive surface functionalization - bioinspired strategies

Mussle adhesion and DOPA

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Surface passivation-antifouling - Motivation

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Surface passivation-antifouling - Facts

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Surface passivation-antifouling - How to avoid protein adsorption

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Surface passivation-antifouling - Self assembled monolayers (SAM)

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Surface passivation-antifouling - Supported lipid bilayers (SLB)

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Surface passivation-antifouling - Polymer brushes-entropic penalty

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Surface passivation-antifouling - Polymer brushes-entropic penalty

Grafting to

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Surface passivation-antifouling - Polymer brushes-entropic penalty

Example PLL-g PEG

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Surface passivation-antifouling - Polymer brushes-entropic penalty

Grafting from

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Surface passivation-antifouling - Other anti-adhesive polymer architecures

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Q

Stability and degradability

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