II. Cells and Materials

Question 1

Cells and tissue - Intro

Question 2

Cells and tissue - Types of tissue

Question 3

Cells and tissue - Types of ECM

Question 4

Cells and tissue - Connective tissue

Question 5

Optimal materials surface - Native ECM

Question 6

Optimal materials surface - Material in contact with cells/Itissues

Question 7

Optimal materials surface - Matierial characteristics and biological stimuli

Question 8

Material-Cell-Tissue Interaction - Bare biomaterials surface

Question 9

Material-Cell-Tissue Interaction - Proteins at hydrophobic surfaces

Question 10

Material-Cell-Tissue Interaction - Proteins at hydrophilic surfaces

Question 11

Material-Cell-Tissue Interaction - Properties of some major plasma protein

Question 12

Cell-substrate adhesive interactions - Intro

Question 13

Cell-substrate adhesive interactions - Attachment dependent cells

Question 14

Cell-substrate adhesive interactions - Attachment dependent cells

Tensegrity

Question 15

Cell-substrate adhesive interactions - Attachment dependent cells

cell attachment and spreading necessary cell behaviour for funtionc –>

Question 16

Cell-substrate adhesive interactions - Tensegrity in cells

Used for:

Question 17

Cell-substrate adhesive interactions - Tensegrity in cells

Mediators of tension

Question 18

Cell-substrate adhesive interactions - Cell adhesion/tension is important for cell proliferation

Question 19

Cell-matrix interactions - Outside in

Question 20

Cell-matrix interactions - Inside-out

Question 21

Cell-matrix interactions - Cell-adhesive matrix proteins

Question 22

Cell-matrix interactions - Extracellular matrix (ECM)

Intro

Question 23

Cell-matrix interactions - Extracellular matrix (ECM)

Highly dynamic

Question 24

Cell-matrix interactions - Extracellular matrix (ECM)

Very complex

Question 25

Cell-matrix interactions - Cell-matrix and cell-cell contracts

Question 26

Cell-matrix interactions - Example

skip

Question 27

Cell-matrix interactions - Integrins

Intro

Question 28

Cell-matrix interactions - Integrins

Known cell adhesion motifs

Question 29

Cell-matrix interactions - Integrin activation

Question 30

Cell-matrix interactions - Focal adhesions

Question 31

Cell adhesion and organization on substrates - Intro

Question 32

Cell adhesion and organization on substrates - Effect of cell spreading on apoptosis

Question 33

Cell adhesion and organization on substrates - Cell proliferation and micropatterns

Question 34

Cell adhesion and organization on substrates - Cell adapt their structure to suit the substrate

Question 35

Cell adhesion and organization on substrates - Cell adapt their behaviour to suit the substrate

Question 36

Cell adhesion and organization on substrates - Cells adapt their phenotype according to their substrate

Question 37

Cell adhesion and organization on substrates - Role of substrate stiffness and ECM component

Question 38

Cell adhesion and organization on substrates - Impact of order and disorder

Question 39

Cell adhesion and organization on substrates - Impact of order and disorder

Relevance

Question 40

Cell adhesion and organization on substrates - Integrins partner with growth factor receptors

Question 41

Engineering cell environment - Designer matrices