II. Cells and Materials Flashcards
Cells and tissue - Intro
Cells and tissue - Types of tissue
Cells and tissue - Types of ECM
Cells and tissue - Connective tissue
Optimal materials surface - Native ECM
Optimal materials surface - Material in contact with cells/Itissues
Optimal materials surface - Matierial characteristics and biological stimuli
Material-Cell-Tissue Interaction - Bare biomaterials surface
Material-Cell-Tissue Interaction - Proteins at hydrophobic surfaces
Material-Cell-Tissue Interaction - Proteins at hydrophilic surfaces
Material-Cell-Tissue Interaction - Properties of some major plasma protein
Cell-substrate adhesive interactions - Intro
Cell-substrate adhesive interactions - Attachment dependent cells
Cell-substrate adhesive interactions - Attachment dependent cells
Tensegrity
Cell-substrate adhesive interactions - Attachment dependent cells
cell attachment and spreading necessary cell behaviour for funtionc –>
Cell-substrate adhesive interactions - Tensegrity in cells
Used for:
Cell-substrate adhesive interactions - Tensegrity in cells
Mediators of tension
Cell-substrate adhesive interactions - Cell adhesion/tension is important for cell proliferation
Cell-matrix interactions - Outside in
Cell-matrix interactions - Inside-out
Cell-matrix interactions - Cell-adhesive matrix proteins
Cell-matrix interactions - Extracellular matrix (ECM)
Intro
Cell-matrix interactions - Extracellular matrix (ECM)
Highly dynamic
Cell-matrix interactions - Extracellular matrix (ECM)
Very complex
Cell-matrix interactions - Cell-matrix and cell-cell contracts
Cell-matrix interactions - Example
skip
Cell-matrix interactions - Integrins
Intro
Cell-matrix interactions - Integrins
Known cell adhesion motifs
Cell-matrix interactions - Integrin activation
Cell-matrix interactions - Focal adhesions
Cell adhesion and organization on substrates - Intro
Cell adhesion and organization on substrates - Effect of cell spreading on apoptosis
Cell adhesion and organization on substrates - Cell proliferation and micropatterns
Cell adhesion and organization on substrates - Cell adapt their structure to suit the substrate
Cell adhesion and organization on substrates - Cell adapt their behaviour to suit the substrate
Cell adhesion and organization on substrates - Cells adapt their phenotype according to their substrate
Cell adhesion and organization on substrates - Role of substrate stiffness and ECM component
Cell adhesion and organization on substrates - Impact of order and disorder
Cell adhesion and organization on substrates - Impact of order and disorder
Relevance
Cell adhesion and organization on substrates - Integrins partner with growth factor receptors
Engineering cell environment - Designer matrices
