IV Procedures And Contrast Flashcards
Contrast agent may help with ?
- Improve the sensitivity and specificity of the clinical diagnosis.
- Differentiate anatomical structures on the images
- Help to define abnormalities on the images.
Any tissue that is perfused, or penetrated, by contrast agent becomes?
More dense
Has an increased ability to attenuate x-ray photons
Correlates with a higher CT number
Will appear brighter on the image
Contrast media that is administered by IV, the tissues that are perfused by the substance include:
Blood vessels
Vascular lesions
Abdominal organs
How to opacity the distal GI tract
Oral agents administered rectally
For a virtual colonoscopy study, what is administered rectally?
Air or CO2
It is ____ in the contrast compounds that is responsible for the increased ability to attenuate x-ray photons.
Iodine
Osmolality is the
Concentration of molecular particles in solution
LOCM has what range of osmolality
500 to 850 mOsm/kg
HOCM has what range of osmolality
1,300 to 1,600 mOsm/kg
Blood has what osmolality
285 mOsm/kg
In general IV contrast agents are ____ (hyper or hypo-osmolar) solutions, or _____ (hyper- or hypo-tonic), compared to blood plasma.
Hyperosmolar
Hypertonic
Hypertonic solutions will cause
A net movement of water from within the tissues, into the vascular space.
This can cause dehydration.
Why is it important to ensure the patient is well hydrated before and after the exam?
Because the contrast media is hypertonic
Viscocity
A measure of the thickness of a liquid, related to the frictional forces of the molecules of the substance as they flow past each other.
A contrast agent will have a high viscocity if it’s…..
Molecular particles are large
What is the significance of contrast with high viscocity ?
- A patient’s tolerance of the force of the injection
2. The kidneys have more difficulty clearing larger molecules from the blood.
Name 11 minor reactions that do not require treatment
Nausea, vomiting, chills, warmth, sweating, minor hives, metallic taste, itching, shaking, headaches, dizziness
Moderate reactions, that may require treatment and close observation, but typically not hospitalization 6
- Moderate hives
- Facial edema
- Change in pulse rate
- Hypo- or hypertension
- Wheezing
- Bronchospasm or laryngospasm
Some scientists group the mechanisms that cause contrast reactions, into 2 categories called:
Chemotoxic
Idiosyncratic
Chemotoxic reaction mechanisms are those that can be directly attributed to factors including:
- Physiological properties
- Total volume injected
- Rate of injection
Osmosis
Is the process in which the contrast particle draw water toward them and away from body tissue or cells
The rapid movement of fluid through osmosis. Into the blood vessels is believed to be contributed to?
- Pain associated with vessel dilation
- Flushing
- Changes to red blood cells
- Vascular endothelium damage
- Vomiting
- Nausea
- Dehydration
How can you reduce the viscosity of contrast?
Warming it
A high concentration of iodine in the contrast agent leads to
- Higher osmolality
2. Higher viscosity
Idiosyncratic reaction mechanisms can be caused by
Anything other than the properties of he contrast agent, the amount injected, or the injection rate.
Adverse reactions that are allergic in nature, means?
The patient’s physiology has trouble tolerating the introduction of a foreign substance. Their body will release histamine
Histamine acts by
- Constricting smooth muscles and venules
- Accelerating heart rate
- Lowering blood pressure
- Increasing gastric and mucous secretions
What happens when an excessive amount of histamine is released in he body?
- The vascular system becomes overloaded and histamine passes into th surrounding tissues.
- Believed to be responsible for reactions such as hypotension and hives
In order to prevent histamine reactions, you can
Pre-medicate with anti-histamine or steroids.
A precaution is?
A condition that would warrant a medical decision as to whether the benefits of the exam outweigh the risks posed to the patient.
A contraindication is
A condition that would preclude a patient from having a study performed in a given manner.
Contraindication to contrast includes
A known hypersensitivity to the compounds (medical history)
Extra caution should be taken with patients with the following precautions
- Liver or kidney disease
- Thyrotoxicosis
3.myelomatosis - Diabetes
- Anuria
- Multiple myeloma
- Sickle cell disease
- Pheochromocytoma
- Hyperthyroidism
10 asthma - Hay fever
- Food allergies
- Congestive heart disease
In normal patients, how long dose it take for 50% of the injected dose is recovered in the urine?
2 hours
In patients with severe renal impairment, how long dose it take for 50% of the injected dose is recovered in the urine?
16 to 84 hours.
Generally patients taking metformin, should not take it after IV contrast, because ?
To prevent lactic acidosis
Metformin should be resumed only after?
Kidney function has been reassessed and determined to be normal.
Patients that take metformin and have renal dysfunction should?
Not take metformin and follow-up renal function tests should be performed until metformin can be taken safely.
Advantages of power-injectors
- Consistent, reproducible flow rate.
- Precise volume and dose control.
- Optimum contrast enhancement is achieved with higher injection rates
- Rates allowed up to 5 or6 ml/sec
What type of needle is not used with a power injector?
Butterfly needle
And
Standard PICC lines (peripherally inserted central catheter)
Specially-labeled Power Piccs may be used with a power injector up to what rate?
5ml/sec
Routine exams use what injection rates
2 to 4 ml/sec
CTA exams use what injection rates
4 to 5 ml/sec