Ischemic Heart Disease Flashcards
What is ischemic heart disease?
Reduction of blood flow to the heart muscle, usually due to CAD=coronary artery disease (artherosclerosis of coronary arteries)
3 symptoms of ischemic heart disease
- Angina (chest pain) - reversible
- MI (plaque ruptures; 20 mins or more angina) - irreversible
- Congestive Heart Failure (lots of damage from MI that it causes heart failure)
Angina Etiology
compromise in coronary blood flow
Angina Signs and symptoms
pain in chest, arms, back, jaw
SOB, diaphoresis (sweat) →w/ MI, get more severe + prolonged chest pains than with angina
Angina prognosis
may progress to MI (usually if pain lasts more than 20 mins its MI)
Angina - nonpharm treatment
- lifestyle modifications
2. risk factor modifications
Angina - 5 meds
- Beta Blockers
- CCB
- Nitrates
- Antiplatelet agents
- Statin
Mechanism of statins
they lower cholesterol levels by inhibiting HMG-CoA reductase enzyme (which produces cholesterol in liver)
What do nitrates do?
Vasodilators, increase coronary blood flow
List 2 nitrates
- Nitrodur
2. Minitran (patches that you put on a night)
What are antiplatelets?
(antiaggregant) decrease platelet aggregation and inhibit thrombus formation.
List 4 statins
- Lovastatin
- Atorvastatin
- Rosuvastatin
- Simvastatin
Hint - Statin
Angina - Treatment surgery
- Coronary Angiography
- Angioplasty and stenting
- Coronary Artery Bypass
Unstable Angina
change in patten of [normal] angina
Treatment of unstable angina
- similar to angina but its a medical emergency
2. admit to hospital