ISBB random recalls Flashcards
what is the ideal body weight for a blood donor?
110 lbs or 50 kg
T/F
Donor’s body weight should be at least 110 lbs (50 kg) or more to remove 450 mL of blood collected in 63 mL of citrate phosphate dextrose (CPD) or citrate phosphate dextrose adenine (CPDA-1) anticoagulant plus up to 30 mL of additional blood used for testing.
T
enumerate the blood groups from most common to least common
O > A > B > AB
cell typing is also known as
forward or direct typing
what is the specimen used for cell typing?
RBCs (Ag)
Enumerate the reagent used (as well as the reagent’s color) in cell typing.
Anti-A (blue: trypan blue)
Anti-B (yellow: acroflavin dye)
Anti-AB (colorless)
serum typing is also known as
reverse or indirect typing
what is the specimen for reverse typing?
serum (Ab)
Enumerate the reagents used for indirect typing.
A1 cells
B cells
the universal donor
group O
the universal recipient
group AB
the universal donor for RBCs
group O (no Ag)
the universal recipient for RBCs
group AB (no Ab)
the universal donor for plasma
group AB (no Ab)
the universal recipient for plasma
group AB (no Ag)
give the percentage range of RCS
2-5% RCS
an RCS approximate should have this distinct color
tomato red color
it differentiate group O from Oh individuals
anti-H
these antibodies are a mixture of IgM, IgG, and IgA
ABO antbodies
mother: group O
baby: group A or B
ABO HDN
mother: Rh (-)
baby: Rh (+), 2nd preggy
Rh HDN
RBCs + anti-D = (+) agglutination
Rh (+)
T/F
here is one of the basic qualifications for potential blood donor:
good health
body weight
- max: 10.5 mL / kg
- ideal: 110 lbs (50kg)
- 450 mL + 30 mL blood (serologic tests)
- 63 mL anticoagulant
T
anticoagulant : blood ration (blood bag)
1:7
if Chris has chagas disease, but he wanted to do his part and donate blood.
a. patient is eligible to donate blood
b. patient is permanently deferred for donating blood.
c. patient has 3 year donor deferral
b
Collecting of new specimen for antibody screening is done every ___ in a series of transfusion.
a. 3 days
b. 7 days
c. 2 days
d. 5 days
a
the donor and recipient samples should be kept for __ days after transfusion at 1-6 degree Celsius.
a. 3 days
b. 7 days
c. 2 days
d. 5 days
b
what are the procedures done when HTR occurs?
- stop transfusion
- keep iv line open
- notify physician & BB
Compatibility testing is a series of tests that ensure safety and of transfusion to recipient and donor.
Can you give at least 3 of these tests?
- review of BB records
- ABO and Rh
- Ab screen
- cross matching
- major x-match = DR/PS
- minor x-match = PR/DS
Immunoglobulin for allergic reactions and parasites
IgE
a type of hypersensitivity reaction when a patient has peanut allergy or asthma
type I
immediate
anaphylactic
main immune mediator: IgE
example of this type of hypersensitivity reactions are SLE, RA, Serum sickness, and Arthus reaction
type III
immune-complex
example of this type of hypersensitivity reactions are skin contact with allergens such as poison ivy or poison oak.
type IV
delayed
cell-mediated
type II sensitivity reaction is also known as
cytotoxic
anti-myelin antibody
MS
anti-glomerular basement membrane antibody
Goodpasture’s syndrome
anti-TSH receptor antibody
grave’s disease
acetylcholine receptor blocking antibody
myasthenia gravis
major cause of post-transfusion hepatitis
MOT: sexual, parenteral, perinatal
flaviviridae (RNA)
HCV
require infection with HBV (superinfection)
HDV
