IS Antigens Flashcards
A substance that reacts with an antibody or sensitized T cells but may not be able to evoke an immune response in the first place?
Antigen
Macromolecules capable of triggering an adaptive immune response by inducing the formation of antibodies or sensitized T cells in an immunocompetent host
Immunogen
Capacity of a compound to bind with antibodies or with cells of the immune system
Antigenicity
Capacity of a compound to induce an immune response
Immunogenicity
Compounds that are part of self are not immunogenic
Foreignness
As immunogens carbohydrates most often occur in the form of?
Glycolipids
Macromolecular size of an immunogen?
10,000 Daltons
Substances that fail to induce immune response in their native form because of their low molecular weight and their chemical simplicity
Haptens
AKA an antigenic determinant and are recognized by B or T cells
Epitopes
2 types of Epitopes
Sequential or Linear and Non-sequential or Conformational
A substance administered with an immunogen that increases the immune response and protects immunogen from degradation
Adjuvants
Antigens that belongs to the host and do not evoke immune response under normal circumstances
Autoantigens
Antigens from other members of the host’s specie and are capable of eliciting immune response
Alloantigens
Antigens from other species
Heteroantigens