Irritable Bowel Syndrome Flashcards
What are the main types of IBS?
- Constipation predominant
- Diarrhea predominant
- Mixed IBS
What is the hallmark of IBS?
Visceral hypersensitivity
What is the difference between IBS and chronic constipation?
Constipation has no pain and IBS does
What is the prevalence of IBS-C (constipation predominant)?
33-50% of IBS patients
What is the prevalence of IBS-D (diarrhea predominant)?
33% of IBS patients
What is IBS-A?
Alternating or Mixed IBS
Where do most patients with IBS first present?
83% of IBS patients first present to their PCP
What is a major discriminating feature with either a change in bowel habits or a disordered defecation.
Prolonged abdominal pain
T/F: Patients presenting with IBS experience relief with defecation.
True
What are the red flags for IBS?
- Age > 50, or an acute or gradual onset in elderly patients
- Hx of anemia/Fe deficiency
- Unintentional weightloss (cachexia)
- FHx of colon cancer, other GI malignanc, or IBD
- Nocturnal smptoms
- Fever
- Oral apthous ulcers
- Hematochezia
- Opthalmic inflammation (iritis/scleritis)
- Dermatologic conditions (erythema nodosum, pyoerma, gangrinosum
- Inflammatory arthritis
What are some of the basic treatments for the different forms of IBS, specifically IBS-D?
Loperamide, Alosetron, Cholestramine resin (ACL)
What are some of the basic treatments for the different forms of IBS, specifically IBS-C?
Psylium husk, Methylcellulose, Calcium polycarbophil, Laculose syrup, 70% Sorbitol, Polyethylene glycol, Lubiprostone, Magnesium hydroxide (CaLM PLuMS)
What are some of the basic treatments for the different forms of IBS, specifically abdominal pain?
Smooth-muscle relaxant, Tricyclic antidepressant, Selective serotonin reuptake inhibitors (STS)
What are other treatment modalities for IBS?
Dietary modifications, Behavioral modifications, Cognitive behavioral therapy
What causes IBS?
Due to abnormal motor function of the GI tract
