Iron Deficiency Anaemia

Question 1

Location of malabsorption in iron absorption

Answer 1

• duodenum

- jejunum

Question 2

Why is acidity required for iron absorption

Answer 2

Keeps iron in ferrous (Fe2+) state

Question 3

Microcytic ID anaemia

Answer 3

RBC w/ less Hb

Question 4

Poikilocytosis ID anaemia

Answer 4

RBC diff shapes

Question 5

Anisocytosis ID anaemia

Answer 5

RBC diff sizes

Question 6

Insufficient dietary iron is the most common cause of IDA in what age group

Answer 6

Children

Question 7

+++ iron requirement is often the cause of IDA in

Answer 7

Pregnant women

Question 8

Iron loss due to bleeding is a common cause of IDA in

Answer 8

Women & periods

Question 9

Inadequate Fe absorption is a common cause of IDA in

Answer 9

GI pathology

Question 10

Impact of PPI on soluble Fe

Answer 10

— since — acid

Question 11

Why are babies & veggies at risk of IDA

Answer 11

• low Fe in milk

- non-haem Fe in vegg harder to absorb

Question 12

IDA specific symptoms

Answer 12

• koilonychia
• hair loss
• pica
• brittle hair & nails

Question 13

Plummer Vinson syndrome features (2)

Answer 13

• atrophic glossitis

- angular chelitis

Question 14

IDA blood film shows (3)

Answer 14

• hypochromic RBCs
• anisopoikilocytosis
• multiple pencil cells

Question 15

Anti-TTG Abs are found in

Answer 15

Coeliac disease patients

Question 16

Low ferritin indicates

Answer 16

Anaemia

Question 17

High ferritin indicates (2)

Answer 17

• inflammation

- iron overload

Question 18

Increased TIBC (total iron binding capacity)

Answer 18

Iron deficiency

Question 19

Decreased TIBC

Answer 19

Iron overload

Question 20

Less saturated transferrin

Answer 20

Less iron

Question 21

More saturated transferred

Answer 21

More iron

Question 22

Fastest —> slowest; most —> least invasive Mx options

Answer 22

• blood transfusions
• iron infusion
• oral iron (ferrous sulphate)

Question 23

Pro & con of blood transfusions

Answer 23

• corrects anaemia

- NOT underlying deficiency

Question 24

Other than anaphylaxis, what other things should u avoid when giving iron infusion

Answer 24

Sepsis

Question 25

Notable side effects of oral iron

Answer 25

• constipation

- black stool

Question 26

Oral iron is contraindicated if IDA is caused by

Answer 26

Malabsorption

Question 27

Patients over the age of 60 who present with iron deficiency anaemia should be investigated for

Answer 27

Colorectal cancer (colonoscopy)

Question 28

Men of any age with a Hb below … should be referred for upper and lower GI endoscopy as a …

Answer 28

• 110g/L

- 2ww