Iron Deficiency Anaemia Flashcards
Location of malabsorption in iron absorption
- duodenum
- jejunum
Why is acidity required for iron absorption
Keeps iron in ferrous (Fe2+) state
Microcytic ID anaemia
RBC w/ less Hb
Poikilocytosis ID anaemia
RBC diff shapes
Anisocytosis ID anaemia
RBC diff sizes
Insufficient dietary iron is the most common cause of IDA in what age group
Children
+++ iron requirement is often the cause of IDA in
Pregnant women
Iron loss due to bleeding is a common cause of IDA in
Women & periods
Inadequate Fe absorption is a common cause of IDA in
GI pathology
Impact of PPI on soluble Fe
— since — acid
Why are babies & veggies at risk of IDA
- low Fe in milk
- non-haem Fe in vegg harder to absorb
IDA specific symptoms
- koilonychia
- hair loss
- pica
- brittle hair & nails
Plummer Vinson syndrome features (2)
- atrophic glossitis
- angular chelitis
IDA blood film shows (3)
- hypochromic RBCs
- anisopoikilocytosis
- multiple pencil cells
Anti-TTG Abs are found in
Coeliac disease patients
Low ferritin indicates
Anaemia
High ferritin indicates (2)
- inflammation
- iron overload
Increased TIBC (total iron binding capacity)
Iron deficiency
Decreased TIBC
Iron overload
Less saturated transferrin
Less iron
More saturated transferred
More iron
Fastest —> slowest; most —> least invasive Mx options
- blood transfusions
- iron infusion
- oral iron (ferrous sulphate)
Pro & con of blood transfusions
- corrects anaemia
- NOT underlying deficiency
Other than anaphylaxis, what other things should u avoid when giving iron infusion
Sepsis
