Iron Flashcards
How much of consumed iron is absorbed?
Very low amounts ~10%
How is non-heme iron absorbed?
What is non-heme iron absorbed as?
By facilitated diffusion
ferrous ions
How is heme iron absorbed?
Vesicle formation
What is removed form heme iron in vesicle formation?
ferrous ions
Heme and Non-heme iron form what to be ferried across the cell and into the blood, via active transport
Ferritin Complexes
What is Non-heme absorption controlled by?
Intestinal Mucosa cells
How do intestinal mucosa cells control the absorption of non-heme iron?
By controlling the amount of iron released in teh blood stream – this is done according to the bodies needs
What influences intestinal mucosa absorption of non-heme iron?
Bodys needs
Hepcidin
Hepcidin?
Hepcidin production is based on?
The effect of Hepcidin is?
nonheme iron regulatory control hormone
produced in the liver based on iron levels and inflammation
Decreased iron absorption
When is the iron absorption downregulated?
When the concentration the body is high
When is iron absorption in the body unregulated?
When the concentration in the body is low
High body iron concentration is known as
Transferrin Saturation
The average absorption rate for iron is about
10%
Absorption of heme iron is effected by dietary components? T/F
F – heme iron is uneffected by dietary components.
absorption of non-heme iron is enhanced by:
Vitamin C
MFP factor (meat pep)
Lactoferrin (breat milk)
Gastric Acid