ipecac Flashcards

1
Q

native name

A

i-pe-kaa-guenem or roadside sick-making plant

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2
Q

type of plant

A

small shrub
30-50 cm in height
understory plant of moist, shady, woodlands in the brazilian highlands and eastern bolivia

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3
Q

related species

A

p. acuminata

occurs in columbia

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4
Q

indigenous ppls

A

used bark of the thickened fibrous root to treat intestinal infections (dysentery)

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5
Q

france 1672

A

samples of powdered ipecac root first appeared

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6
Q

paris merchant garnier

A

imported 70kg in 1680

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7
Q

jean-adrien helvetius

A

successfully treated members of the french royal family, and cure the heir to the throne (dauphin) of dysentry

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8
Q

helevetius was granted the sole rights to the use of ipecac by

A

louis XIV

-1699 he sold rights to the french government

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9
Q

botanical source of ipecac unknown until

A

1880, when Portuguese physician gomez first brought the plant to europe

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10
Q

thomas dover

A

in england developed dovers powder
a mixture of ipecac,opium and other substances sold as a treatment for fever, gout and dysentry
dovers powder and other ipecac syrups popular in the 18th century

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11
Q

ipecac used as a very powerful emetic

A

a substance that induces vomiting and was commonly administered to children as a purgative

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12
Q

moderate doses of ipecac were used to induce

A

perspiration and as an expectorant in treating bronchitis, and small doses were recommended as a digestive stimulant

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13
Q

active principles

A

alkaloids emetine and cephaeline

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14
Q

ipecac root is an effective treatment for amoebic dysentery (amoebiasis but its powerful…

A

emetic properties (characterized by vomiting and diarrhea) limit its use

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15
Q

emetine and cephaelin

A

cause inflammation of the peripheral nerves, irregular heartbeat, sudden lowering of blood pressure and extreme cases sudden death

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16
Q

much safer treatments for amoebic dysentery

A

diloxanide (for intestinal ameobiasis)
metronidazol (for hepatic ameobiasis)
semi synthetic dehydroemetine

17
Q

until recently

A

ipecac syrup was also used as an emergency emetic: it induces vomiting expelling from the stomach accidentally ingested irritants and non caustic poisons -this se is now actively discourages, since much safer emetics are available.

18
Q

ipecac has also been used in aversion therapy

A

treating chronic alcoholism