ipecac Flashcards
native name
i-pe-kaa-guenem or roadside sick-making plant
type of plant
small shrub
30-50 cm in height
understory plant of moist, shady, woodlands in the brazilian highlands and eastern bolivia
related species
p. acuminata
occurs in columbia
indigenous ppls
used bark of the thickened fibrous root to treat intestinal infections (dysentery)
france 1672
samples of powdered ipecac root first appeared
paris merchant garnier
imported 70kg in 1680
jean-adrien helvetius
successfully treated members of the french royal family, and cure the heir to the throne (dauphin) of dysentry
helevetius was granted the sole rights to the use of ipecac by
louis XIV
-1699 he sold rights to the french government
botanical source of ipecac unknown until
1880, when Portuguese physician gomez first brought the plant to europe
thomas dover
in england developed dovers powder
a mixture of ipecac,opium and other substances sold as a treatment for fever, gout and dysentry
dovers powder and other ipecac syrups popular in the 18th century
ipecac used as a very powerful emetic
a substance that induces vomiting and was commonly administered to children as a purgative
moderate doses of ipecac were used to induce
perspiration and as an expectorant in treating bronchitis, and small doses were recommended as a digestive stimulant
active principles
alkaloids emetine and cephaeline
ipecac root is an effective treatment for amoebic dysentery (amoebiasis but its powerful…
emetic properties (characterized by vomiting and diarrhea) limit its use
emetine and cephaelin
cause inflammation of the peripheral nerves, irregular heartbeat, sudden lowering of blood pressure and extreme cases sudden death