Introduction to Vascular System Flashcards
3 main types of vessels that carry blood around the body
- ) Arteries and Arterioles
- ) Veins
- ) Capillaries
Arteries
Carry blood away from the heart
Carry oxygen rich blood in the systemic circuit
Carry oxygen poor blood in pulmonary circuit
Veins
Carry blood back to the heart
Carry oxygen poor blood in systemic circuit
Carry oxygen rich blood in pulmonary circuit
Capillaries
Exchange materials between blood and cells. Location of gas and nutrient exchange between blood and tissues
All vessels will be lined with
A thin layer of endothelium - which is a type of epithelium which is supported by a basement membrane. Called tunica intima.
Tunica Intima
Or endothelium. Innermost tunica (layer) of an artery or vein
Only layer that is present in capillaries
Tunica Media (Surrounds endothelium)
Circularly arranged smooth muscle fibers.
Tunica Externa (surrounds endothelium)
Outermost layer, Fibrous connective tissue.
Thickness of Tunica Media/Externa
Vary in vessels depending on location or amount of blood pressure they encounter. A large artery close to heart will have thick tunica media/externa bc they have to resist high pressures coming from the pump or heart.
Heart can be thought of as 2 separate pumps
One originating from the right ventricle and the second originating from the left ventricle.
From the right ventricle blood will be pumped at low pressure to lungs and after it undergoes gas exchange it will be pumped back to left atria. From left atria, it will go to left ventricle
From right Atria
blood will be pumped at low pressure to lungs and after it undergoes gas exchange, oxygen rich blood it will be pumped back to left atria through pulmonary vein. So from right atrium to right ventricle deoxygentated blood enters pulmonary circulation.
rom left atria
Oxygenated blood will go to left ventricle (second pump). Blood is pumped at a high pressure . It goes up through ascending aorta to the rest of the body. eventually we will return to cardiac circulation at right atria
Pulmonary circulation requires
thin tunica intima (endothelium) for gas exchange. Dont want to thicken up for gas exchange.
Branches off the aorta
Branches off the aorta will ascend up to the head and neck region. Critical for day to day function and development. Head and neck need first dibs on oxygenated blood.
Further pathways of oxygenated blood
Goes to portal circulation (gastrointestinal) and lower regions of body.
Portal Circulation
GI tract. Unique because two capillary bedss linked by a vein prior to returning to the heart. The first capillary bed will be associated with the GI wall and the second capillary bed will be the system within the liver.
Arterial Map
Arteries have divergent blood flow - upon departing the ventricles a single artery splits into numerous arteries with smaller diameters. Arterioles will eventually split into capillaries. Capillaries will be most numerous blood vessel (smallest diameter) that contains only tunica intima
Venous Map
Veins have convergent blood flow. Blood flows from many capillaries and congregates on a single venule. Our venules evetually become veins with larger and larger diameters so merging to one single vessel that allows for blood to go back to right atria. (thru inferior and superior vena cava)
Distribution of Blood
Distribution of systemic blood varies according to the metabolic needs of the individual organs and is governed by homeostatic reflexes. ex: after a meal we are going to push more blood into GI tract to allow for absorprtion of nutrients to blood.
- Skeletal muscles at rest receive 21% of cardiac output
- Exercising skeletal muscle receives 85% of cardiac output
- vasoconstriction and vasodilation of arterioles (how we diverge more or less blood)
The lymphatic system
Large network of tissues and organs that help alleviate the body of all of its toxins and waste. Primary function is to transport lymph. This system mimics venous system.
Ex: Looking at the inguinal region - the inguinal lymph nodes will occur along femoral vein, great saphenous vein, etc.
lymph vessels run with veins but hard to see bc of thin walls. so blend with venous system.
able to see in abdomen by vertebral bodies and heart.
Lymph
fluid that Contains infection fighting wbcs.. So in a case with a large inflammatory response we will have more wbcs present in lymph.
in lymphoma - cancer cells can enter this stream of drainage. how metastatic cells transfer from one region to the next.
Spleen
major exporter of wbc in lymphatic system. If have cancer, will be quite large
bone marrow
major factory for development of wbc’s
tonsils
major dev. of wbc’s
thymus
functions in dev of wbcs during infancy and atrophies away in adulthood. Major pre processing center of T cells
Thoracic duct
By vertebrae. major lymphatic highway of the entire body. Lower extremities, abdomen, pelvis, and left upper body will deposit all their lymphatic frainage to thoracic duct
Lymphatic duct
right upper body will deposit lymphatic drainage to lymphatic duct (on right side). opens directly to subclavian or brachiocephalic vein on right side.
cisterna chyli
that it receives and temporarily stores lymph, the clear body tissue fluid, as it traverses upwards the body. … The upper part of the Cisterna Chyli stretches to the thoracic duct and drains in the left subclavian vein.