Introduction to Neuroanatomy Flashcards
What is the study of the brain and nervous system?
Neuroscience
Branch of medicine concerned with the anatomy of the nervous system
Neuroanatomy
How do you know if someone is having a stroke?
FAST
- Facial Drooping
- Arm Weakness
- Speech difficulties
- Time to call emergency services
Where is Substantia nigra located?
Found in the midbrain, related to Parkinson’s disease
What plane divides the body into left and right?
Sagittal Plane
What plane divides the body into anterior and posterior?
Frontal Plane / Coronal Plane
What plane divides the body in the superior and inferior?
Transverse Plane / Horizontal Plane / Axial Plane
Basis of linear orientation of nervous system
Fish and reptiles
What refers to “beak” end? Refers to the anterior in human brain.
Rostral
What refers to “tail” end? Refers to the posterior in human brain.
Caudal
What do you call the rostral-caudal central nervous system axis?
Neuraxis
What is the “belly” side (towards the earth)?
Ventral
What is the “back” side (towards the sky)?
Dorsal
In humans, neuraxis is deformed to a __________.
Right angle
How do you differentiate the anterior and posterior between the brain and the rest of the body?
Brain: Anterior = Rostral, Posterior = Caudal
Body: Anterior = Ventral, Posterior = Dorsal
These cells transmit nerve impulses along nerve fibers:
Neurons
Nerves are made up of _________.
Nerve fibers
Components of the Central Nervous System (CNS)
Brain and spinal cord
Components of Peripheral Nervous System (PNS)
Cranial nerves and ganglia, spinal nerves and dorsal root ganglia, sympathetic and parasympathetic nerves and ganglia
Consciously controlled
Somatic
Unconsciously controlled
Autonomic
What are the functions of the nervous system?
- Integration of body processes
- Control of voluntary effectors
- Control of involuntary effectors
- Response to stimuli
- Conscious thoughts and perceptions
Approach to studying neuroanatomy that describes the brain’s evolution from simple to complex creatures
Comparative
Approach to studying neuroanatomy that examines the development within an individual. it correlates emerging behaviors with developing brain.
Developmental
Approach to studying neuroanatomy that describes architecture of cells.
Cytoarchitecture / Cytoarchitectonic
A region of the cortex defined based on its cytoarchitecture and named after Korbinian Brodmann
Brodmann Area
Approach to studying neuroanatomy that describes intercellular communication (neurotransmitters)
Biochemical
Describe Parkinsonism
Low levels of dopamine in brain happens when nerve cells in a part of the brain that makes dopamine breaks down.
Approach to studying neuroanatomy that questions effects on functions upon damage.
Functional neuroanatomy
Approach to studying neuroanatomy that localizes structures in particular brain regions.
Regional neuroanatomy
What are the non-invasive brain imaging methods?
- CT scan (Computerized Tomography)
- MRI (Magnetic Resonance Imaging)
- fMRI (Functional MRI)
- PET Scan (Positron Emission Tomography)
It uses x-rays to produce brain images with low resolution used for viewing structures.
CT scan (Computer tomography)
What tissue is seen as a dark area (hypodensity) in the brain CT scan?
Ischemic Brain
What tissue is seen as a light area (hyperdensity) in the brain CT scan?
Hemorrhagic Brain
What is the mechanism of having dark/light areas in a CT scan?
Dense areas prevent passage of x-ray, preventing it from burning the film (turning it into black).
Through which plane can CT scan only cut through?
Axial Plane / Horizontal Plane / Transverse Plane
Which non-invasive brain imaging is limited by thickness?
CT scan
In terms of information given and resolution, differentiate the 4 non-invasive brain imaging methods.
CT scan - Structure, low resolution
MRI - Structure, high resolution
fMRI - Function, high resolution
PET - Function, low resolution
Some non-imaging methods to study the brain:
Autopsy
Electrical stimulation
EEG (Electroencephalogram)
Which embryonic germ layer does the CNS and PNS originate from?
Ectoderm
Which embryonic germ layer does the notochord come from?
Mesoderm
Steps from ectoderm to neural canal
Ectoderm -> Neuroectoderm -> Neural Plate -> Neural Groove -> Neural tube w/ neural canal
Embryonic origin of the brain (specific)
Rostral end of neural tube
Embryonic origin of the spinal cord (specific)
Caudal end of neural tube
What are the primary vesicles and their corresponding secondary vesicles?
Prosencephalon (forebrain) -> Telencephalon, Diencephalon
Mesencephalon (midbrain) -> Mesencephalon
Rhombencephalon (hindbrain) -> metencephalon, Myelencephalon
What are the neural derivatives of the secondary vesicles?
Telencephalon: Cerebral cortex, White matter, Basal Ganglia, Hippocampus, Amygdala
Diencephalon: Thalamus, Hypothalamus, Subthalamus, Epithalamus
Mesencephalon: Midbrain
Metencephalon: Cerebellum, Pons
Myelencephalon: Medulla oblongata
Outermost, durable connective tissue covering the brain with many blood vessels
Dura matter
Forms the periosteum of the skull bones
Dura matter
Avascular covering of the brain that does not follow its convolutions
Arachnoid matter
Covering that is closest to the brain, often adherent and difficult to remove because it follows the contours of the brain and spinal cord. It contains many blood vessels and nerves.
Pia matter
Space between dura matter and arachnoid matter
Subdural space