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Animal Tech IV - Pocket Pets > Introduction to Lab Medicine > Flashcards

Introduction to Lab Medicine Flashcards

1
Q

A field of science devoted to the production, care, and study of lab animals used in biomedical research and education

A

Lab Animal Science

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2
Q

The first person to experiment on living animals

A

Aristotle

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3
Q

Developed the germ theory by introducing anthrax to sheep

A

Louis Pasteur

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4
Q

The theory that microorganisms cause disease

A

Germ Theory

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5
Q

90-95% of research animals

A

Mice and rats

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6
Q

Used dogs to describe classical conditioning

A

Ivan Pavlov

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7
Q

Developed the polio vaccine using rhesus macaques

A

Jonas Salk

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8
Q

The first mammal successfully cloned from adult cells

A

Dolly the sheep

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9
Q

The primary species of fish used in research

A

Zebra fish

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10
Q

Used for flu research

A

ferrets

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11
Q

Large company that breeds animals for research

A

Charles River

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12
Q

Company that produces rodents for research

A

JAX

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13
Q

Company that produces NHPs for research (Non-human primates)

A

Alphagenesis

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14
Q

Goats and sheep are primarily used in research for

A

cardio research

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15
Q

Used with emetic research

A

shrews

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16
Q

Found in horseshoe crab blood as opposed to HgB

A

hemocyanin

17
Q

The American Veterinarian Medical Association

A

AVMA

18
Q

American Association for Lab Science

Certifies at 3 levels

A

AALAS

19
Q

A book published by the Institute of Lab Animal Resources

A

The Guide for the Care and Use of Lab Animals

20
Q

Institutional Animal Care and Use Committee
Consists of a vet, an outside member, a practicing scientist, and a member with no scientific background
Announced inspections 2x a year
Reviews and okays protocols

A

IACUC

21
Q

How long are protocols good for?

A

3 years

22
Q

Written document that explains the use of animals, how many, and why they are needed

A

protocols

23
Q

United States Department of Agriculture
Does unannounced inspections of facilities once a year
Looks at record keeping, ID of animals, and procedures completed

A

USDA

24
Q

Associations for Assessment and Accreditation of Lab Animals Care
Private, nonprofit organization
Promotes humane treatment of animals in science through VOLUNTARY accreditation and assessment programs
Commited to responsible animal care and use
Inspections every 3 years

A

AAALAC

25
Q

Mandated by the USDA

Protects non-farm animals

A

Animal Welfare Act

26
Q

3 certification classifications for AALAS

A
  1. ALAT
  2. LAT
  3. LATG
27
Q

The 3 R’s

A
  1. Replacement
  2. Reduction
  3. Refinement
28
Q

The 3 R’s were developed by

A

Russell and Burch

29
Q

Consist of a combination of lab practices and techniques, safety equipment, and lab facilities
Each combo is specific to the operations performed

A

Biosafety Levels

30
Q

This BSL is not known to consistently cause dz in immunocompetent adults

Ex: E. coli

A

BSL 1

31
Q

This BSL is associated with human disease.
Hazardous: percutaneous, MM exposure, and ingestion

Ex: Hepatitis and HIV

A

BSL 2

32
Q

This BSL is associated with indigenous or exotic agents with potential for aerosol transmission
Dz has serious or lethal consequence
Must have PPE on at all times, and there should be a negative pressure airflow through the lab
Double door access

Ex: tuberculosis

A

BSL 3

33
Q

This BSL consists of dangerous/exotic agents which pose high risk of life-threatening dz
Clothing must be changed before entering and you must shower upon exit
Should be in a seperate building or isolated zone and have it’s own dedicated supply/exhaust, vacuum, and decon system

Ex: Ebola virus

A

BSL 4

Animal Tech IV - Pocket Pets (8 decks)

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