Introduction to FPP Flashcards
what are the 2 types of connections between cells?
electrical synapses and chemical synapses
what are electrical synapses?
cells are physically connected together and there is a pathway through one cell to another
what are chemical synapses?
action potential causes the release of a transmitter which interacts w receptor molecules
what is paracrine signalling?
a chemical is released from a cell and diffuses to neighbouring cells and interacts w the receptors
what is endocrine signalling?
a chemical is released from a cell and travels through the blood stream to reach it’s target
what is synaptic signalling?
a neuronal conduction or neuromuscular junction
what are the 4 types of proteins that influence the solubility of the cell?
- receptors
- ion channels
- transporters
- enzymes
what are receptors?
- proteins that have a binding site for a chemical
- causes rapid change in events
- 2 types: cell-surface and intracellular
describe ion channels
-‘protonatious’ pores that have a gating mechanism-highly sensitive w high transfer rate
how ion channels classified?
1) the permeant ion: whether is selective or non-selective
2) the gating mechanism: voltage, mechanical, ligand
what are examples of voltage gated ion channels?
- Na+ channels
- K+ channels
- Ca2+ channels
- Cl- channels
what are transporters and give an example?
exchangers where one ion is swapped for another
how are Ca2+ levels maintained in the cytoplasm?
- Na+/Ca2+ exchanger
- Ca2+ pump
- Ca2+ binding molecule
