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CYTOGEN > INTRODUCTION TO BIOINFORMATICS > Flashcards

INTRODUCTION TO BIOINFORMATICS Flashcards

1
Q

With this, we can submit the discovered biological data and store and organize such data

A

Bioinformatics

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2
Q

It is a field which uses computers to store and analyze molecular biological information

A

Bioinformatics

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3
Q

It is about finding and interpreting biological data online.

A

Bioinformatics

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4
Q

It is the application of tools of computation and analysis to the capture and interpretation of
biological data

A

Bioinformatics

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5
Q

Give the 3 principal components of Bioinformatics

A
  1. Creation of databases
  2. The development of algorithms and statistics
  3. The use of these tools for the analysis and interpretation of various types of biological data
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6
Q

They are repository or like banks, this is where we store or gather biological information

A

Databases

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7
Q

These are designed to collect, archive, visualize, or arrange the biological information

A

Databases

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8
Q

It helps or enables the scientist in the retrieval of data that they will be needing for their research

A

Databases

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9
Q

It serves as a benchmark in the ongoing discovery of the molecular basis for disease, and this is the groundwork for molecular diagnostics

A

Human genome project

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10
Q

It is a branch of bioinformatics that study about RNA molecules in a living organisms

A

Transcriptomics

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11
Q

In this branch of bioinformatics, the genomes of bacteria, viruses, fungi, or parasites are described within a specific environment

A

Microbiomics

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12
Q

In this branch of bioinformatics, it involves the description of the chemical processes involving metabolites

A

Metabolomics

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13
Q

In this branch of bioinformatics, it describes the sequences of the WHOLE genome of an organisms

A

Genomics

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14
Q

In this branch of bioinformatics, it describes the entire complement of proteins in the entire organisms

A

Proteomics

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15
Q

it is done in a computer instead of a real laboratory

A

In silico

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16
Q

Protein Database in USA

A

RCSB PDB

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17
Q

This databases contains original data in the form or primary sequence data or structural data as submitted by the scientific community

A

Primary Databases

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18
Q

This database contain biomolecular data in its original form.

A

Primary databases

19
Q

This database contains information that has been processed and derived from the raw data available in primary database

A

Secondary database

20
Q

Contains data derived from the results of
analyzed primary data or from the raw data.

A

Secondary databases

21
Q

It is a way of rearranging sequences of DNA, RNA, or protein to identify regions of similarity

A

Sequence alignment

22
Q

It is the known sequence

A

reference sequence

23
Q

It is the unknown sequence

A

query sequence

24
Q

give the 2 types of sequence alignment

A

Pairwise and multiple

25
Q

Give the tools used in pairwise

A

EMBOSS Water and BLAST

26
Q

Give the tools used in Multiple Sequence alignment

A

MUSCLE, MAFFT, CLUSTAL Omega

27
Q

A type of pairwise sequence alignment that Matching the residues (bases or amino acids)
of two sequences across their entire length

A

Global Aalignment

28
Q

it Matches the identical sequences from 5’ to 3’

A

Global Alignment

29
Q

The two sequences are treated as potentially equivalent

A

Global Alignment

30
Q

It represents gap, which means there is presence in the first sequence and the second has none

A

dash line

31
Q

it means the first sequence is identical/similar to second sequence

A

Straight line

32
Q

A type of pairwise sequence alignment that Matching of two sequences from regions
which have more similarity with each other

A

Local Alignment

33
Q

In this type of pairwise sequence, the two sequences may or may not be related

A

Local Alignment

34
Q

True or False:
In global alignment, the whole
sequence is aligned, whereas in local alignment, only a portion/part is aligned.

A

True

35
Q

In EMBOSS WATER, dissimilar bases are indicated by?

A

dot

36
Q

It is the analysis of more than two sequences

A

Multiple Alignment Tools

37
Q

It is a multiple sequence alignment tool that is used to directly compare the sequences to one another

A

CLUISTAL OMEGA

38
Q

in clustal omega, same color in one column means?

A

Similar

39
Q

It is a multiple sequence alignment tool that arranges the sequences of DNA, RNA, or protein to identify regions of similarity

A

MUSCLE

40
Q

This tool is used to find regions of local similarity between sequences

A

BLAST (Basic Local Alignment Search Tool)

41
Q

It is used to compare the unknown sequence with the database

A

Blast

42
Q

nucleotide to nucleotide aligment

A

Blastn

43
Q

protein to protein alignment

A

Blastp

CYTOGEN (11 decks)

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