Introduction And Model Organisms Flashcards
What are multi-potential stem cells?
Can produce a restricted range of cell types.
What are pluripotent stem cells?
Found in embryos, have unrestricted developmental potential (except extra embryonic tissues)
What is pattern formation?
Where a developing organism has to create organised differences in field of cells where different genes have been expressed
What are the four approaches to understanding developmental biology?
- Descriptive embryology
- Experimental embryology
- Developmental genetics
- Molecular mechanisms
What are the four main developmental processes?
- Pattern formation
- Morphogenesis
- Cell differentiation
- Growth
What are the four essential cell behaviours?
- Cell proliferation
- Cell specialisation
- Cell interactions
- Cell movement
What makes cells different?
- Inductive signals
- Lateral inhibition
- Asymmetric cell division
What are model organisms?
A non-human species used to understand biological processs.
What features are required in model organisms?
- Able to produce embryos that are numerous, large, accessible , rapidly developing
- east to manipulate gene function, determine expression profile of genes, localisation of protein
- Transparent
- good model for human development
- reasonable cost and ease of maintenance in lab
- Short generation time
What is the conceptual tool kit?
External signals> transcription factors> genes > proteins> cell properties> developmental processes
