Intro To Virology 1 Flashcards

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1
Q

Are all of our cells able to contract a virus except red blood cells?

A

Yes

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2
Q

Linnaean system is used to…

A

Classify viruses

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3
Q

Why are viruses not cells?

A

Cant propagate independently
Only propagate inside living cells
Completely parasitic

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4
Q

What are obligate intercellular parasites?

A

Viruses

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5
Q

Viruses are not alive

A

Inert unless inside a permissive cell

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6
Q

Viruses do not grow apart from expansion in rod or helical viruses

A

Fixed size

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7
Q

Do viruses divide?

A

No
Duplicate their component bio molecules
They replicate

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8
Q

Are viruses suseptible to antibiotics?

A

No

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9
Q

Viruses have NO mitochondria

A

No biochemical energy machinery

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10
Q

Viruses have no ribosomes

A

No protein synthesis machines

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11
Q

Capsid

A

Hollow protein structure
Protects from desication , uv light
Bond to proteins on surface of cell

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12
Q

Nucleocapsid

A

Complete binding of the helix of the genome with protein

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13
Q

Enzymes

A

Proteins carried inside virion or encoded by genome

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14
Q

Capsid helical shape

A

Rod shape

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15
Q

Capsid icosahedral 20 triangular sides

A

Cone HIV, regular geometric shape, of 1,2,3 or more types of proteins

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16
Q

Membrane envelope will have proteins encoded

A
17
Q

How do proteins get to a membrane?

A

Pass through ER and Golgi
Are modified
Generally glycosylated

18
Q

Membrane (envelope) have large..

A

Glycostructures on outside

19
Q

Glycoproteins are embedded in the…

A

Virion envelope

20
Q

Space between membrane and envelope of a virus is called…

A

Tegument (loose association)
Matrix (close-fitting structure (matrix)

21
Q

Genome show diversity in…

A

Size
Composition (RNA OR DNA. Single or multiple chromosomes)
Conformation (single or double stranded. Circular or linear)
Gene coding strategy (on both or 1 strand) positive, negative or ambi-sense
Gene copy number (haploid, merodiploid, diploid)

22
Q

Coding strand has a complimentary..

A

Template strand

23
Q

Gene-sense strand is

A

Positive - sense
Duplicated as messenger RNA
Take sequence to ribosomes

24
Q

Template strand / complementary strand carries the…

A

Reverse complement of the coding sequence (negative sense)

25
Q

Nucleotide sequence of coding region is referred to as…

A

SENSE

26
Q

In our cells we can only transcribe RNA from a DNA template

A

RNA polymerase work from DNA strand

27
Q

Viruses which are RNA strands have to have…

A

Their own version of RNA polymerase to make new RNA

28
Q

All viruses must replicate 2 complementary nuclei acid strands

A

Even if genome is single stranded

29
Q

Transcription begins at…

A

Promoter sequences

30
Q

Messenger RNAs have to be transcribed to make..

A

Proteins, then translated on ribosomes

31
Q

Depending on what enzymes used to make mRNA’s it will dictate…

A

How well they bind to ribosomes