Intro To Virology 1 Flashcards
Are all of our cells able to contract a virus except red blood cells?
Yes
Linnaean system is used to…
Classify viruses
Why are viruses not cells?
Cant propagate independently
Only propagate inside living cells
Completely parasitic
What are obligate intercellular parasites?
Viruses
Viruses are not alive
Inert unless inside a permissive cell
Viruses do not grow apart from expansion in rod or helical viruses
Fixed size
Do viruses divide?
No
Duplicate their component bio molecules
They replicate
Are viruses suseptible to antibiotics?
No
Viruses have NO mitochondria
No biochemical energy machinery
Viruses have no ribosomes
No protein synthesis machines
Capsid
Hollow protein structure
Protects from desication , uv light
Bond to proteins on surface of cell
Nucleocapsid
Complete binding of the helix of the genome with protein
Enzymes
Proteins carried inside virion or encoded by genome
Capsid helical shape
Rod shape
Capsid icosahedral 20 triangular sides
Cone HIV, regular geometric shape, of 1,2,3 or more types of proteins
Membrane envelope will have proteins encoded
How do proteins get to a membrane?
Pass through ER and Golgi
Are modified
Generally glycosylated
Membrane (envelope) have large..
Glycostructures on outside
Glycoproteins are embedded in the…
Virion envelope
Space between membrane and envelope of a virus is called…
Tegument (loose association)
Matrix (close-fitting structure (matrix)
Genome show diversity in…
Size
Composition (RNA OR DNA. Single or multiple chromosomes)
Conformation (single or double stranded. Circular or linear)
Gene coding strategy (on both or 1 strand) positive, negative or ambi-sense
Gene copy number (haploid, merodiploid, diploid)
Coding strand has a complimentary..
Template strand
Gene-sense strand is
Positive - sense
Duplicated as messenger RNA
Take sequence to ribosomes
Template strand / complementary strand carries the…
Reverse complement of the coding sequence (negative sense)
