Intro To Pharm

Question 1

How many new Rx drugs introduced in the last 3 years

Answer 1

70

Question 2

Covers a variety of disciplines to explain the molecular mechanisms of action of drugs. These include: biochemistry, pathophysiology, molecular biology, and organic chemistry

Answer 2

Pharmacology

Question 3

The molecular process of a drug initiates a cascade of events that produce an effect detectable by the following

Answer 3

• instruments (blood pressure)
• laboratory tests on body fluids or tissue samples
• direct observation of the patient by the physician

Question 4

Things to consider when choosing a drug

Answer 4

1. Patient-to-patient
2. Life-threatening situation
3. The status of the patient may change
4. Use of multiple drugs, some elderly patients taking up to 12 drugs, can have drug interactions

Question 5

What do you need to make the proper drug selection

Answer 5

Experience and an element of experiment

Question 6

The study of the interaction of chemicals with living systems

Answer 6

Pharmacology

Question 7

Substances that act on living systems at the chemical (molecular) level

Answer 7

Drug

Question 8

The molecular components of the body with which a drug interacts to bring about its effect

Answer 8

Drug receptors

Question 9

The study of drugs used for the diagnosis, prevention, and treatment of disease

Answer 9

Medical pharmacology

Question 10

The study of the undesirable effects of chemical agents on living systems; considered an area of pharmacology; in addition to the adverse effects of therapeutic agents on individuals, it also deals with the action of industrial pollutants, natural organic and inorganic poisons, and other chemicals on species and ecosystems

Answer 10

Toxicology

Question 11

Refers to the actions of a drug on the body, including receptor interaction, dose-response, phenomena, and mechanisms of therapeutic and toxic action

Answer 11

Pharmacodynamics

Question 12

Refers to the actions of the body on the drug, including absoprtion, distribution, metabolism and excretion; elimination of a drug may be achieved by metabolism or by excretion

Answer 12

Pharmacokinetics

Question 13

The ratio of the dose of drug that produces toxicity in 50% of the population to the dose that produces a clinically desired or effective response in 50% of the population

Answer 13

Therapeutic index (margin of safety)

Question 14

Is a higher or lower number better for a therapeutic index?

Answer 14

Higher, the smaller the number, the easier it is to be toxic. If the number is 2, they only have to take double the dose to have a toxic effect. .

Question 15

TI=

Answer 15

TD50/ED50

Question 16

For most drugs, the magnitude of the ___________ increases as the concentration of the drug at the site of action increases. The converse is also true when the drugs actions are reversible

Answer 16

Pharmacological response

Question 17

What are the 3 drug name types

Answer 17

Chemical, generic, trade. Will be tested on generic/trade

Question 18

Old pregnancy classification of drugs

Answer 18

ABCDX, with A being safe, D and X being the worst

Question 19

What is the new pregnancy drug classifications

Answer 19

A narrative, asking about breastfeeding and such