Intro to O2 therapy Flashcards

1
Q

Too much O2 will damage what? Physiological damage

A
  • increased free radical leading to oxidative damage to vital organs
  • mucosal inflammation
  • cillia inactivation
  • hemolysis
  • desctruction of Type I pneumocytes
  • increased production of Type II pnuemocytes
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2
Q

O2 Toxicity occurs at what levels?

A

375mmHg with FiO2~0.50 over 14hrs

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3
Q

O2 therapy precautions

A
  • affects lungs at clinical PO2 levels- patchy infiltrates on x-ray in lower lung
    CNS- hyperbaric pressures
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4
Q

pathophysiology; too much O2?

A
  • damage capillary endothelium
  • interstitial edema
  • AC memberane thickiening
  • changes in levels of type I and type II pneumocytes
  • shunting–> hypoxemia
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5
Q

Increased metabolism by O2

A
  • increased cellular byproducts than antioxidants can clean up
  • recruit neutrophils (WBC)–> more inflammation and free radicals
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6
Q

Absorption Atelactasis

A
  • nitrogen washout
  • no non- diffusing gas remain in the lungs
  • when O2 leaves, the alveoli will be vacant and collapsed
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7
Q

O2 hazards

A
  • increased risk for fire

- cautious when using electronic equipment, scalpels, cardioconversion, cardio shock

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8
Q

Nasal Cath

A

FiO2: 0.24-0.44 with flow of 1-6LPM. 4% increases forver 1LPM inrease
- for babies

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9
Q

Nasal Canula

A

FiO2: 0.24-0.44 with flow of 1-6LPM. 4% increases forver 1LPM inrease

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10
Q

Simple mask

A

5-8LPM; FiO2 .40-.60

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11
Q

High flow NC

A

1-15LPM replaces PRBM

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12
Q

PRBM

A

6-15LPM (usually start at 10LPM); FiO2 0.60-0.80 and up

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13
Q

NRBM

A

8-15LPM; FiO2>0.80

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14
Q

Trans Tracheal Cathter

A

for difficult airways

placed through cricoid cartliage or between second and third tracheal ring

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15
Q

Oxymask

A

1-15LPM;FiO2 0.24-0.90

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16
Q

Low flow O2 devices

A
  • Variable FiO2

- does not meet total inspiratory demands of patients

17
Q

Percent O2 in atmosphere

18
Q

What is O2 used for

A

ATP production, angiogenesis, vasodilation/ vasoconstriction, suppress anaerobic bacteria

19
Q

Hypoxia

A

inadequate O2 for cellular metabolism

20
Q

hypoxemia

A

low blood O2 levels

21
Q

causes of hypoxemia

A

decreased alveolar oxygen tension, increased altitude, inadequate ventilation (hypopnea, apnea)

22
Q

Hypoxemia by shunt

A

perfusion no ventilation

23
Q

hypoxemia via deapspace

A

ventilation without perfusion

24
Q

response to hypoxemia

A

Increased MV, increased Cardiac output, Increased production of RBCs

25
signs and symptoms of hypoxemia
cyanosis, arrythmia, disorientation, polycythemia (high Hb - more chronic), lethargy
26
4 types of Hypoxia
hypoxic, anemic, ciruculatory, histotoxic
27
hypoxic hypoxia
not enough O2 in cells | responds to O2 therapy
28
circulatory hypoxia
normal blood O2 levels but not enough blood reaching the tissues NO response to O2 therapy
29
histotoxiic hypoxia
Sufficient blood O2 levels and O2 delivered but inability of the tissues to use O2. e.g. CN poisoning NO respose to O2 therapy
30
anemic hypoxia
not enough RBC to deliver O2 to tissues. Either due to RBC deformity, CO poisoning. May respond to O2 therapy